Evidence map›Paper›PMID 24901330›Full record

ArticleThe Journal of head trauma rehabilitation

Improved Cardiorespiratory Fitness With Aerobic Exercise Training in Individuals With Traumatic Brain Injury.

Lisa M K Chin, Leighton Chan, Joshua G Woolstenhulme, Eric J Christensen, Christian N Shenouda, Randall E Keyser

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02504866 (Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients With Traumatic Brain Injury), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02504866 naterminatednot on this map

Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients With Traumatic Brain Injury

TypeinterventionalSponsorNational Institutes of Health Clinical Center (CC)Ran2016 to 2020Enrolled20ConditionsTraumatic Brain Injury (TBI)ArmsVigorous exercise, Light to moderate exercise
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  15. Perceived Barriers to Exercise in Adults with Traumatic Brain Injury Vary by Age.Journal of functional morphology and kinesiology · 2018
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lisa M K ChinDepartment of Rehabilitation Science, George Mason University, Fairfax, Virginia (Drs Chin, Woolstenhulme, and Keyser); and Rehabilitation Medicine Department, National Institutes of Health Clinical Center (Drs Chin, Chan, Woolstenhulme, and Keyser and Mr Christensen), and Center for Neuroscience and Regenerative Medicine (Drs Chan and Shenouda), Bethesda, Maryland.
Leighton Chan
Joshua G Woolstenhulme
Eric J Christensen
Christian N Shenouda
Randall E Keyser

Funding

Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

objectiveTo examine cardiorespiratory fitness in individuals with traumatic brain injury (TBI), before and following participation in a supervised 12-week aerobic exercise training program.

methodsTen subjects with nonpenetrating TBI (TBI severity: mild, 50%; moderate, 40%; severe, 10%; time since injury [mean ± SD]: 6.6 ± 6.8 years) performed exercise training on a treadmill 3 times a week for 30 minutes at vigorous intensity (70%-80% of heart rate reserve). All subjects completed a cardiopulmonary exercise test, with pulmonary gas exchange measured and a questionnaire related to fatigue (Fatigue Severity Scale) at baseline and following exercise training.

resultsAfter training, increases (P < .01) in peak oxygen consumption ((Equation is included in full-text article.); +3.1 ± 2.4 mL/min/kg), time to volitional fatigue (+1.4 ± 0.8 minutes), and peak work rate (+59 ± 43 W) were observed. At the anaerobic threshold, (Equation is included in full-text article.)(+3.6 ± 2.1 mL/kg/min), treadmill time (+1.8 ± 1.1 minutes), and work rate (+37 ± 39 W) were higher (P < .01) following exercise training. Subjects also reported significantly lower (P < .05) Fatigue Severity Scale composite scores (-0.9 ± 1.3) following exercise training.

conclusionThese findings suggest that individuals with TBI may benefit from participation in vigorous aerobic exercise training with improved cardiorespiratory fitness and diminished fatigue.

Indexed as

Quality of LifeAdultBrain InjuriesCohort StudiesExerciseExercise TestExercise ToleranceFatigueFemaleFollow-Up StudiesHumansMaleOxygen ConsumptionPhysical FitnessPredictive Value of TestsProspective Studies

Identifiers

PMID24901330
PMCPMC4685937

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.