ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Novelty enhances visual salience independently of reward in the parietal lobe.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 67 citations in OpenAlex.
- Conceptual priorities shape individual gaze patterns during naturalistic visual attention.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Sustained visual signals in the primate cerebellar dentate nucleus drive associative learning.Communications biology · 2025Article
- Curiosity: primate neural circuits for novelty and information seeking.Nature reviews. Neuroscience · 2024Review
- Memory capacity and prioritization in female mice.Scientific reports · 2023Article
- Salience memories formed by value, novelty and aversiveness jointly shape object responses in the prefrontal cortex and basal ganglia.Nature communications · 2022Article
- How the value of the environment controls persistence in visual search.PLoS computational biology · 2021Article
- Human complex exploration strategies are enriched by noradrenaline-modulated heuristics.eLife · 2021Article
- Anterior Cingulate Cortex and the Control of Dynamic Behavior in Primates.Current biology : CB · 2020Review
- Reward uncertainty asymmetrically affects information transmission within the monkey fronto-parietal network.Communications biology · 2020Article
- Saccade vigor and the subjective economic value of visual stimuli.Journal of neurophysiology · 2020Article
- Distinguishing pain from nociception, salience, and arousal: How autonomic nervous system activity can improve neuroimaging tests of specificity.NeuroImage · 2020Review
- Visual fixation patterns during economic choice reflect covert valuation processes that emerge with learning.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Novelty, Salience, and Surprise Timing Are Signaled by Neurons in the Basal Forebrain.Current biology : CB · 2019Article
- Responses of Neurons in Lateral Intraparietal Area Depend on Stimulus-Associated Reward During Binocular Flash Suppression.Frontiers in systems neuroscience · 2019Article
- Towards a neuroscience of active sampling and curiosity.Nature reviews. Neuroscience · 2018Review
- Bridging Neural and Computational Viewpoints on Perceptual Decision-Making.Trends in neurosciences · 2018Review
- Understanding active sampling strategies: Empirical approaches and implications for attention and decision research.Cortex; a journal devoted to the study of the nervous system and behavior · 2018Review
- Visual Responses in FEF, Unlike V1, Primarily Reflect When the Visual Context Renders a Receptive Field Salient.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Parietal neurons encode expected gains in instrumental information.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Perceptual suppression of predicted natural images.Journal of vision · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Novelty modulates sensory and reward processes, but it remains unknown how these effects interact, i.e., how the visual effects of novelty are related to its motivational effects. A widespread hypothesis, based on findings that novelty activates reward-related structures, is that all the effects of novelty are explained in terms of reward. According to this idea, a novel stimulus is by default assigned high reward value and hence high salience, but this salience rapidly decreases if the stimulus signals a negative outcome. Here we show that, contrary to this idea, novelty affects visual salience in the monkey lateral intraparietal area (LIP) in ways that are independent of expected reward. Monkeys viewed peripheral visual cues that were novel or familiar (received few or many exposures) and predicted whether the trial will have a positive or a negative outcome--i.e., end in a reward or a lack of reward. We used a saccade-based assay to detect whether the cues automatically attracted or repelled attention from their visual field location. We show that salience--measured in saccades and LIP responses--was enhanced by both novelty and positive reward associations, but these factors were dissociable and habituated on different timescales. The monkeys rapidly recognized that a novel stimulus signaled a negative outcome (and withheld anticipatory licking within the first few presentations), but the salience of that stimulus remained high for multiple subsequent presentations. Therefore, novelty can provide an intrinsic bonus for attention that extends beyond the first presentation and is independent of physical rewards.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.