ArticleJournal of nephrology2015
Associations of dietary macronutrients with glomerular filtration rate and kidney dysfunction: Tehran lipid and glucose study.
Article in Journal of nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Association between dietary protein intake and risk of chronic kidney disease: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts.BMJ (Clinical research ed.) · 2023Pooled it
- Sugar- and artificially-sweetened beverages and the risks of chronic kidney disease: a systematic review and dose-response meta-analysis.Journal of nephrology · 2021Pooled it
- Individualized Diets in Patients with Kidney Disease and Kidney Transplants: A Narrative Review.Life (Basel, Switzerland) · 2025Review
- Plant-Based Diets across the Spectrum of Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2025Review
- New developments in epidemiological research on dietary patterns associated with chronic kidney disease.Frontiers in nutrition · 2025Review
- Oat-Protein-Based Diet Lowers Blood Pressure and Prevents Cardiac Remodeling and Dysfunction in Spontaneously Hypertensive Rats.Nutrients · 2024Article
- Plant-based diets in patients with chronic kidney disease.Asian biomedicine : research, reviews and news · 2024Review
- Urinary Na/K ratio is a predictor of developing chronic kidney disease in the general population.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Is there any association between type of dietary fat and quality of life in hemodialysis patients? A cross-sectional study.Frontiers in nutrition · 2024Article
- Vegetarian Nutrition in Chronic Kidney Disease.Nutrients · 2023Review
- Analysis of different plant- and animal-based dietary patterns and their relationship with serum uric acid levels in Chinese adults.Nutrition journal · 2023Article
- The Burden of Carbohydrates in Health and Disease.Nutrients · 2022Review
- Prospective associations between a priori dietary patterns adherence and kidney function in an elderly Mediterranean population at high cardiovascular risk.European journal of nutrition · 2022Article
- Associations between dietary patterns and stages of chronic kidney disease.BMC nephrology · 2022Article
- Article
- High Dietary Diabetes Risk Reduction Score Is Associated with Decreased Risk of Chronic Kidney Disease in Tehranian Adults.International journal of clinical practice · 2022Article
- Dietary protein score and carbohydrate quality index with the risk of chronic kidney disease: Findings from a prospective cohort study.Frontiers in nutrition · 2022Article
- Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure.iScience · 2021Article
- Dietary acid load and risk of cardiovascular disease: a prospective population-based study.BMC cardiovascular disorders · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough dietary components may play a role in the development of chronic kidney disease (CKD), data on this topic are scarce. The objective of this study was to investigate the association between macronutrient intakes and CKD in a large non-diabetic adult population-based study.
methodsThis cross-sectional study recruited 5,316 participants aged ≥27 years without diabetes within the framework of the Tehran lipid and glucose study. Dietary intake was collected using a validated food-frequency questionnaire. Macronutrients intake including total-, animal-, and plant-protein, carbohydrate, simple sugar, fructose, total fat, saturated fatty acids, poly- and monounsaturated-fatty acids (PUFA and MUFA), and n-3 and n-6 fatty acids was categorized into quartiles. Anthropometrics, blood pressure, serum creatinine, and fasting plasma glucose and lipids were measured. Estimated glomerular filtration rate (eGFR) was calculated using the Modification of Diet in Renal Disease Study equation. CKD was defined as eGFR <60 ml/min/1.73 m(2).
resultMean age of participants was 45.0 ± 12.2 years. Mean eGFR was 71.9 ± 11.1 ml/min/1.73 m(2), and 13% had CKD. After adjustment for serum triglycerides and cholesterol, body mass index, and hypertension, the risk of CKD decreased in the highest quartile compared to lowest quartile of plant protein (OR, 95% CI) (0.70, 0.51-0.97), PUFA (0.73, 0.55-0.99), and n-6 fatty acids (0.75, 0.57-0.97). However, the risk of CKD increased in the highest quartile of animal protein (1.37, 1.05-1.79) compared to the lowest.
conclusionPlant protein, PUFA, and n-6 fatty acids are associated with a lower risk of CKD, independently of hypertension and diabetic mellitus, while animal protein may be a risk factor for CKD in adults.
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