Evidence map›Paper›PMID 24899076›Full record

Trial reportAlcohol and alcoholism (Oxford, Oxfordshire)

Effectiveness of nurse-practitioner-delivered brief motivational intervention for young adult alcohol and drug use in primary care in South Africa: a randomized clinical trial.

Jennifer R Mertens, Catherine L Ward, Graham F Bresick, Tina Broder, Constance M Weisner

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Alcohol and alcoholism (Oxford, Oxfordshire). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03205449 (Parenting for Lifelong Health-Philippines), which is not on this map. Cited by 36 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 11 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03205449 nacompletednot on this map

Parenting for Lifelong Health-Philippines: Randomized Controlled Trial of a Culturally-adapted Parenting Program on Reducing the Risk of Violence Against Children in Low-income Filipino Families With Children Aged 2 to 6 Years in Manila

TypeinterventionalSponsorAteneo de Manila UniversityRan2017 to 2019Enrolled120ConditionsChild MaltreatmentArmsMasayang Pamilya Para Sa Batang Pilipino Parenting Programme (MaPa), Parenting Effectiveness Service
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 11 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Brief Drug Interventions Delivered in General Medical Settings: a Systematic Review and Meta-analysis of Cannabis Use Outcomes.Prevention science : the official journal of the Society for Prevention Research · 2025
    Pooled it
  2. Motivational interviewing for substance use reduction.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Effectiveness of brief alcohol interventions in primary care populations.The Cochrane database of systematic reviews · 2018
    Pooled it
  11. Research in the Integration of Behavioral Health for Adolescents and Young Adults in Primary Care Settings: A Systematic Review.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2017
    Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jennifer R MertensKaiser Permanente Northern California, Oakland, CA, USA jennifer.mertens@kp.org.
Catherine L WardDepartment of Psychology, University of Cape Town, Cape Town, South Africa.
Graham F BresickSchool of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Tina BroderNational Viral Hepatitis Roundtable, San Francisco, CA, USA.
Constance M WeisnerLangley Porter Psychiatric Institute, University of California San Francisco, San Francisco, CA, USA Division of Research, Kaiser Permanente, Oakland, CA, USA.
Kaiser Permanente · USUniversity of Cape Town · ZA

Funding

Integrated Drug and Medical Care-Cost and EffectivenessR37DA010572 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISNER, CONSTANCE M. · 2001 to 2010
$4.7M
Long-term Opioid Management of Chronic Pain: Trends and RisksR01DA022557 · NIDA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2006 to 2009
$2.4M
Brief Intervention to Reduce Substance Use in South African Primary CareR21DA022430 · NIDA · KAISER FOUNDATION RESEARCH INSTITUTE · PI MERTENS, JENNIFER RENE · 2007 to 2008
$317k
NIDA NIH HHS R21 DA022430NIDA NIH HHS R21DA022557NIDA NIH HHS R37 DA010572
6 · The paper itself

Abstract

aimsTo assess the effectiveness of brief motivational intervention for alcohol and drug use in young adult primary care patients in a low-income population and country.

methodsA randomized controlled trial in a public-sector clinic in Delft, a township in the Western Cape, South Africa recruited 403 patients who were randomized to either single-session, nurse practitioner-delivered Brief Motivational Intervention plus referral list or usual care plus referral list, and followed up at 3 months.

resultsAlthough rates of at-risk alcohol use and drug use did not differ by treatment arm at follow-up, patients assigned to the Brief Motivational Intervention had significantly reduced scores on ASSIST (Alcohol, Smoking and Substance Involvement Screening Test) for alcohol-the most prevalent substance.

conclusionBrief Motivational Intervention may be effective at reducing at-risk alcohol use in the short term among low-income young adult primary care patients; additional research is needed to examine long-term outcomes.

Indexed as

Motivational InterviewingNurse PractitionersPsychotherapy, BriefAdolescentFemaleHumansMalePovertyPrimary Health CareSingle-Blind MethodSouth AfricaSubstance-Related DisordersTreatment OutcomeYoung Adult

Identifiers

PMID24899076
PMCPMC4060738
OpenAlexW2315396724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.