ArticleBMC cardiovascular disorders2014
Comorbidity profiles and inpatient outcomes during hospitalization for heart failure: an analysis of the U.S. Nationwide inpatient sample.
Article in BMC cardiovascular disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review of Medical Costs Associated with Heart Failure in the USA (2014-2020).PharmacoEconomics · 2020Pooled it
- Trends in prevalence of comorbidities in heart failure clinical trials.European journal of heart failure · 2020Pooled it
- Characterising Multimorbidity in Adults With Heart Failure: A Latent Class Analysis.Heart, lung & circulation · 2026Article
- Ten-Year Trends in Clinical Profiles, Management, and Outcomes of De Novo Acute Heart Failure.Journal of clinical medicine · 2026Article
- Association between albumin-corrected calcium and all-cause mortality in patients with heart failure: a retrospective study.Frontiers in cardiovascular medicine · 2025Article
- Characteristics and outcomes of inpatients aged 85 and older with thoracolumbar vertebral fractures: impact on hospital stay and mortality.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Assessment of ICD eligibility in non-ischaemic cardiomyopathy patients: a position statement by the Task Force of the Dutch Society of Cardiology.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024Review
- Clusters of Comorbidities in the Short-Term Prognosis of Acute Heart Failure among Elderly Patients: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2022Article
- Hierarchical management of chronic heart failure: a perspective based on the latent structure of comorbidities.ESC heart failure · 2022Article
- Update on the Impact of Comorbidities on the Efficacy and Safety of Heart Failure Medications.Current heart failure reports · 2021Review
- Incremental prognostic value of cardiac metaiodobenzylguanidine imaging over the co-morbid burden in acute decompensated heart failure.ESC heart failure · 2021Article
- Crucial considerations: Sex differences in the epidemiology, diagnosis, treatment, and outcomes of acute pulmonary embolism in non-pregnant adult patients.Journal of the American College of Emergency Physicians open · 2021Review
- Model-based comorbidity clusters in patients with heart failure: association with clinical outcomes and healthcare utilization.BMC medicine · 2021Article
- Relation of a Simple Cardiac Co-Morbidity Count and Cardiovascular Readmission After a Heart Failure Hospitalization.The American journal of cardiology · 2020Article
- Metabolic Alterations in Inherited Cardiomyopathies.Journal of clinical medicine · 2019Review
- Increasing Economic Burden in Hospitalized Patients With Cirrhosis: Analysis of a National Database.Clinical and translational gastroenterology · 2019Article
- High N-Terminal proB-Type Natriuretic Peptide Indicates Elevated Risk of Death after Percutaneous Coronary Intervention Compared to Coronary Artery Bypass Surgery in Patients with Left Ventricular Dysfunction.Journal of clinical medicine · 2019Article
- Complex Lower Extremity Wound in the Complex Host: Results From a Multicenter Registry.Plastic and reconstructive surgery. Global open · 2019Article
- High-Risk Comorbidity Combinations in Older Patients Undergoing Emergency General Surgery.Journal of the American Geriatrics Society · 2019Article
- Readmission and mortality in patients ≥70 years with acute myocardial infarction or heart failure in the Netherlands: a retrospective cohort study of incidences and changes in risk factors over time.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundTreatment of heart failure (HF) is particularly complex in the presence of comorbidities. We sought to identify and associate comorbidity profiles with inpatient outcomes during HF hospitalizations.
methodsLatent mixture modeling was used to identify common profiles of comorbidities during adult hospitalizations for HF from the 2009 Nationwide Inpatient Sample (n = 192,327).
resultsMost discharges were characterized by "common" comorbidities. A "lifestyle" profile was characterized by a high prevalence of uncomplicated diabetes, hypertension, chronic pulmonary disorders and obesity. A "renal" profile had the highest prevalence of renal disease, complicated diabetes, and fluid and electrolyte imbalances. A "neurovascular" profile represented the highest prevalence of cerebrovascular disease, paralysis, myocardial infarction and peripheral vascular disease. Relative to the common profile, the lifestyle profile was associated with a 15% longer length of stay (LOS) and 12% greater cost, the renal profile was associated with a 30% higher risk of death, 27% longer LOS and 24% greater cost, and the neurovascular profile was associated with a 45% higher risk of death, 34% longer LOS and 37% greater cost (all p < 0.001).
conclusionsComorbidity profiles are helpful in identifying adults at higher risk of death, longer length of stay, and accumulating greater costs during hospitalizations for HF.
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