ReviewPaediatric drugs2014
The pharmacologic management of delirium in children and adolescents.
Review in Paediatric drugs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Non-pharmacological interventions for delirium in the pediatric population: a systematic review with narrative synthesis.BMC pediatrics · 2024Pooled it
- Psychomotor Rehabilitation for Pediatric Delirium: A Study Protocol for a Randomized Controlled Trial Investigating Efficacy and Brain Electrophysiological Mechanisms.Neuropsychiatric disease and treatment · 2026Article
- Non-pharmacological interventions for delirium in critically ill children: a scoping review.BMJ open · 2025Article
- The Challenges of Diagnosing, Managing, and Preventing Pediatric Delirium.Children (Basel, Switzerland) · 2025Review
- Delirium in the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- Article
- Assessment and Management of Delirium in the Pediatric Intensive Care Unit: A Review.Journal of pediatric intensive care · 2023Review
- The Use of Psychotropic Medication in Pediatric Oncology for Acute Psychological and Psychiatric Problems: Balancing Risks and Benefits.Children (Basel, Switzerland) · 2022Review
- Psychological and Psychiatric Comorbidities in Youth with Serious Physical Illness.Children (Basel, Switzerland) · 2022Review
- Evaluation of Pediatric Delirium Awareness and Management in Pediatric Intensive Care Units in Turkey.Journal of pediatric intensive care · 2022Article
- High-Dose Dexmedetomidine for Severe Hyperactive Delirium Secondary to Intravenous Levetiracetam on Two Separate Occasions in the Same Patient.Case reports in psychiatry · 2022Article
- Practice Variability in Screening and Treating Pediatric Critical Illness Delirium: Survey.Journal of pediatric intensive care · 2021Article
- Current State of Analgesia and Sedation in the Pediatric Intensive Care Unit.Journal of clinical medicine · 2021Review
- The stability of quetiapine oral suspension compounded from commercially available tablets.PloS one · 2021Article
- Opioid use is Associated with ICU Delirium in Mechanically Ventilated Children.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2020Article
- Management of Hyperactive Delirium in the Pediatric Intensive Care Unit: Case Series of Three Young Children.Journal of pediatric intensive care · 2020Article
- Sleep and Delirium in Pediatric Critical Illness: What Is the Relationship?Medical sciences (Basel, Switzerland) · 2018Review
- Pediatric Delirium: Evaluation, Management, and Special Considerations.Current psychiatry reports · 2017Review
- Evaluation of the Safety of Quetiapine in Treating Delirium in Critically Ill Children: A Retrospective Review.Journal of child and adolescent psychopharmacology · 2015Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delirium is a serious and common problem in severely medically ill patients of all ages. It has been less addressed in children and adolescents. Treatment of delirium is predicated on addressing its underlying cause. The management of its symptoms depends on the off-label use of antipsychotics, while avoiding agents that precipitate or worsen delirium. Olanzapine, quetiapine, and risperidone are presently considered first-line drugs, usually replacing haloperidol. Other agents have shown promise, including melatonin to address the sleep disturbance characteristic of delirium, and dexmedetomidine, an α2-agonist, that may facilitate lower doses of benzodiazepines and opioids that may worsen delirium.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.