Evidence map›Paper›PMID 24897277›Full record

ArticlePharmacogenomics2014

Warfarin pharmacogenetic trials: is there a future for pharmacogenetic-guided dosing?

Stuart A Scott, Steven A Lubitz

Abstract readEditorial
In one paragraph

Article in Pharmacogenomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. In Vivo Functional Effects ofDrug metabolism and disposition: the biological fate of chemicals · 2021
    Article
  2. Article
  3. A path to precision in the ICU.Critical care (London, England) · 2017
    Review
  4. Article
  5. Article
  6. Article
  7. Contrasting Medical and Legal Standards of Evidence: A Precision Medicine Case Study.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2016
    Article
  8. Genes affecting warfarin response-interactive or additive?Journal of clinical pharmacology · 2015
    Article
  9. Article
  10. Revisiting Warfarin Dosing Using Machine Learning Techniques.Computational and mathematical methods in medicine · 2015
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stuart A ScottDepartment of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1497, New York, NY 10029, USA.
Steven A Lubitz

Funding

Atrial Fibrillation: Bridging genetic discovery and clinical associationsK23HL114724 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LUBITZ, STEVEN A · 2013 to 2017
$893k
The Pharmacogenomic Control of Clopidogrel Response in Acute Coronary SyndromesK23GM104401 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCOTT, STUART ALEXANDER · 2013 to 2016
$778k
NHLBI NIH HHS K23 HL114724NHLBI NIH HHS K23HL114724NIGMS NIH HHS K23 GM104401NIGMS NIH HHS K23GM104401
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical Trials as TopicHumansInternational Normalized RatioPharmacogeneticsRandomized Controlled Trials as TopicWarfarinWarfarinclinical utilityCYP2C9pharmacogeneticspharmacogenomicsrandomized controlled clinical trialVKORC1warfarin

Identifiers

PMID24897277
PMCPMC4110075

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.