Evidence map›Paper›PMID 24895624›Full record

Observational studyBioMed research international2014

Acoustic radiation force impulse elastography for efficacy evaluation after hepatocellular carcinoma radiofrequency ablation: a comparative study with contrast-enhanced ultrasound.

Xiaohong Xu, Liangping Luo, Jiexin Chen, Jiexin Wang, Honglian Zhou, Mingyi Li, Zhanqiang Jin, Nianping Chen, Huilai Miao, Manzhou Lin and 3 more

Open access · hybridAbstract readComparative StudyObservational Study
In one paragraph

Observational study in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Transcatheter embolization therapy in liver cancer: an update of clinical evidences.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Xiaohong XuThe First Affiliated Hospital of Jinan University, Guangzhou 510632, China ; The Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Liangping LuoThe First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Jiexin ChenThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Jiexin WangThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Honglian ZhouThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Mingyi LiThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Zhanqiang JinThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Nianping ChenThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Huilai MiaoThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Manzhou LinThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Wei DaiThe Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
Anil T AhujaDepartment of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Yi-Xiang J WangDepartment of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
Guangdong Medical College · CNFirst Affiliated Hospital of Jinan University · CNChinese University of Hong Kong · CNPrince of Wales Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo explore acoustic radiation force impulse (ARFI) elastography in assessing residual tumors of hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA). MATERIALS AND

methodsThere were 83 HCC lesions among 72 patients. All patients were examined with ARFI, contrast enhanced ultrasound (CEUS), and CT or MRI. Tumor brightness on virtual touch tissue imaging (VTI) and shear wave velocity (SWV) were assessed before and approximately one month after RFA.

resultsThere were 14 residual tumors after RFA. VTI showed that all the tumors were darker after RFA. VTI was not able to distinguish the ablated lesions and the residual tumors. 13 residual tumor lesions were detected by CEUS. All completely ablated nodules had SWV demonstration of x.xx., while with those residual nodules, 6 tumors had x.xx measurement and 8 tumors had measurable SWV. nine lesions with residual tumors occurred in cirrhosis subjects and 5 lesions with residual tumors occurred in fibrosis subjects; there was no residual tumor in the normal liver subjects.

conclusionVTI technique cannot demonstrate residual tumor post RFA. While SWV measurement of less than x.xx is likely associated with residual tumors, measurement of less than x.xx cannot exclude residual tumors. Liver cirrhosis is associated with decreased chance of a complete ablation.

Indexed as

Catheter AblationContrast MediaUltrasonicsCarcinoma, HepatocellularElasticity Imaging TechniquesHumansLiver NeoplasmsNeoplasm, ResidualTreatment OutcomeContrast Media

Identifiers

PMID24895624
PMCPMC4033335
OpenAlexW2122011042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.