Evidence map›Paper›PMID 24895607›Full record

ReviewBioMed research international2014

Application of proteomics and peptidomics to COPD.

Girolamo Pelaia, Rosa Terracciano, Alessandro Vatrella, Luca Gallelli, Maria Teresa Busceti, Cecilia Calabrese, Cristiana Stellato, Rocco Savino, Rosario Maselli

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Prognostic Biomarkers Based on Proteomic Technology in COPD: A Recent Review.International journal of chronic obstructive pulmonary disease · 2023
    Review
  6. Review
  7. Application of Proteomics in Sarcoidosis.American journal of respiratory cell and molecular biology · 2020
    Review
  8. Article
  9. [COPD: An early disease].Revue de pneumologie clinique · 2016
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Sirtuin 1 and aging theory for chronic obstructive pulmonary disease.Analytical cellular pathology (Amsterdam) · 2015
    Review
  17. Integrative genomics of chronic obstructive pulmonary disease.Biochemical and biophysical research communications · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Girolamo PelaiaDepartment of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
Rosa TerraccianoDepartment of Health Science, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
Alessandro VatrellaDepartment of Medicine and Surgery, University of Salerno, Salerno, Italy.
Luca GallelliDepartment of Health Science, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
Maria Teresa BuscetiDepartment of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
Cecilia CalabreseDepartment of Respiratory Medicine, Second University of Naples, Caserta, Italy.
Cristiana StellatoDepartment of Medicine and Surgery, University of Salerno, Salerno, Italy.
Rocco SavinoDepartment of Health Science, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
Rosario MaselliDepartment of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) is a complex disorder involving both airways and lung parenchyma, usually associated with progressive and poorly reversible airflow limitation. In order to better characterize the phenotypic heterogeneity and the prognosis of patients with COPD, there is currently an urgent need for discovery and validation of reliable disease biomarkers. Within this context, proteomic and peptidomic techniques are emerging as very valuable tools that can be applied to both systemic and pulmonary samples, including peripheral blood, induced sputum, exhaled breath condensate, bronchoalveolar lavage fluid, and lung tissues. Identification of COPD biomarkers by means of proteomic and peptidomic approaches can thus also lead to discovery of new molecular targets potentially useful to improve and personalize the therapeutic management of this widespread respiratory disease.

Indexed as

Bronchoalveolar LavageHumansPeptidesProteomicsPulmonary Disease, Chronic ObstructiveRespirationSputumPeptides

Identifiers

PMID24895607
PMCPMC4026877

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.