ArticleBioMed research international2014
BAG3 and HIF-1 α coexpression detected by immunohistochemistry correlated with prognosis in hepatocellular carcinoma after liver transplantation.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease.International journal of molecular sciences · 2022Article
- Understanding Myocardial Metabolism in the Context of Cardio-Oncology.Heart failure clinics · 2022Review
- HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy.The Journal of clinical investigation · 2022Article
- H2A Histone Family Member Z (H2AFZ) Serves as a Prognostic Biomarker in Lung Adenocarcinoma: Bioinformatic Analysis and Experimental Validation.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- BAG3 induces α-SMA expression in human fibroblasts and its over-expression correlates with poorer survival in fibrotic cancer patients.Journal of cellular biochemistry · 2022Article
- Therapeutic targeting of BAG3: considering its complexity in cancer and heart disease.The Journal of clinical investigation · 2021Review
- Long noncoding RNA network: Novel insight into hepatocellular carcinoma metastasis (Review).International journal of molecular medicine · 2021Review
- Intrahepatic recurrence of hepatocellular carcinoma after resection: an update.Clinical journal of gastroenterology · 2021Review
- Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer.Molecular oncology · 2019Article
- miR-424-5p represses the metastasis and invasion of intrahepatic cholangiocarcinoma by targeting ARK5.International journal of biological sciences · 2019Article
- H2A.Z regulates tumorigenesis, metastasis and sensitivity to cisplatin in intrahepatic cholangiocarcinoma.International journal of oncology · 2018Article
- Down-regulation of BAG3 inhibits proliferation and promotes apoptosis of glioblastoma multiforme through BAG3/HSP70/HIF-1α signaling pathway.International journal of clinical and experimental pathology · 2018Article
- γ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition.Oncotarget · 2015Article
- TAZ regulates cell proliferation and epithelial-mesenchymal transition of human hepatocellular carcinoma.Cancer science · 2015Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective is to determine the effects of BAG3 and HIF-1 α expression on the prognosis of HCC patients after liver transplantation.
methodsSamples from 31 patients with HCC receiving liver transplantation were collected for this study. The immunohistochemistry was used to detect the expression of BAG3 and HIF-1 α of HCC samples.
resultsAccording to the immunohistochemistry results, BAG3 and HIF-1 α staining were significantly associated with tumor TNM stage (P = 0.004, P = 0.012). A significant association between high BAG3/HIF-1 α levels and a shorter overall survival was detected, so as the combined BAG3 and HIF-1 α analysis.
conclusionThe results suggested that the expression level of BAG3 and HIF-1 α is efficient prognostic parameters in patients with HCC after liver transplantation.
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