ReviewBiochemistry research international2014
Microbial tyrosinases: promising enzymes for pharmaceutical, food bioprocessing, and environmental industry.
Review in Biochemistry research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 169 citations in OpenAlex.
- Extraction, Purification, and Biochemical Characterization of Tyrosinase from Agaricus bisporus: An Important Enzyme in Biotechnology Applications.Applied biochemistry and biotechnology · 2026Article
- Microbial melanin: biosynthesis, functional Insights, and emerging research challenges.World journal of microbiology & biotechnology · 2026Review
- Exploring the Potential of Morus nigra L. Fruit and Leaves as Food Additives: Antioxidant, Antiproliferative, Enzyme Inhibition Effects, and Phytochemical Profiles.Chemistry & biodiversity · 2026Article
- Analysis of femoroacetabular impingement by a triade of label-free optical spectroscopy techniques.Communications biology · 2025Article
- Inhibition effects of Eucalyptus globules Labill. essential oil against tyrosinase.Scientific reports · 2025Article
- Adaptation strategies in haloalkaliphilic fungi: Aspergillus salinarum, cladosporium sphaerospermum, and penicillium camemberti.BMC microbiology · 2025Article
- Natural pigments derived from plants and microorganisms: classification, biosynthesis, and applications.Plant biotechnology journal · 2025Review
- Sources and Applications of Tyrosinase in Life Sciences.Current pharmaceutical biotechnology · 2025Review
- Exploring the Agricultural Applications of Microbial Melanin.Microorganisms · 2024Review
- Biochemical andMedicinal chemistry (Shariqah (United Arab Emirates)) · 2024Article
- Potent inhibition of human tyrosinase inhibitor by verproside from the whole plant ofJournal of enzyme inhibition and medicinal chemistry · 2023Article
- Article
- Tyrosinase Inhibitors: A Perspective.Molecules (Basel, Switzerland) · 2023Review
- Tissue engineering modalities in skeletal muscles: focus on angiogenesis and immunomodulation properties.Stem cell research & therapy · 2023Review
- Design, Synthesis, In Vitro, and In Silico Insights of 5-(Substituted benzylidene)-2-phenylthiazol-4(5Molecules (Basel, Switzerland) · 2023Article
- A Comprehensive Review of Food Hydrogels: Principles, Formation Mechanisms, Microstructure, and Its Applications.Gels (Basel, Switzerland) · 2022Review
- Screening and Structure-Activity Relationship for Selective and Potent Anti-Melanogenesis Agents Derived from Species of Mulberry (GenusMolecules (Basel, Switzerland) · 2022Review
- Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: a critical review on a structure-activity relationship.Journal of enzyme inhibition and medicinal chemistry · 2022Review
- Use of soil actinomycetes for pharmaceutical, food, agricultural, and environmental purposes.3 Biotech · 2022Review
- Nomilin from Yuzu Seed Has In Vitro Antioxidant Activity and Downregulates Melanogenesis in B16F10 Melanoma Cells through the PKA/CREB Signaling Pathway.Antioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tyrosinase is a natural enzyme and is often purified to only a low degree and it is involved in a variety of functions which mainly catalyse the o-hydroxylation of monophenols into their corresponding o-diphenols and the oxidation of o-diphenols to o-quinones using molecular oxygen, which then polymerizes to form brown or black pigments. The synthesis of o-diphenols is a potentially valuable catalytic ability and thus tyrosinase has attracted a lot of attention with respect to industrial applications. In environmental technology it is used for the detoxification of phenol-containing wastewaters and contaminated soils, as biosensors for phenol monitoring, and for the production of L-DOPA in pharmaceutical industries, and is also used in cosmetic and food industries as important catalytic enzyme. Melanin pigment synthesized by tyrosinase has found applications for protection against radiation cation exchangers, drug carriers, antioxidants, antiviral agents, or immunogen. The recombinant V. spinosum tryosinase protein can be used to produce tailor-made melanin and other polyphenolic materials using various phenols and catechols as starting materials. This review compiles the recent data on biochemical and molecular properties of microbial tyrosinases, underlining their importance in the industrial use of these enzymes. After that, their most promising applications in pharmaceutical, food processing, and environmental fields are presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.