Evidence map›Paper›PMID 24895525›Full record

ArticleOxidative medicine and cellular longevity2014

Effects of heat acclimation on changes in oxidative stress and inflammation caused by endurance capacity test in the heat.

Triin Kaldur, Jaak Kals, Vahur Ööpik, Mihkel Zilmer, Kersti Zilmer, Jaan Eha, Eve Unt

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Triin KaldurInstitute of Exercise Biology and Physiotherapy, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia ; Estonian Centre of Behavioural and Health Sciences, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia.ORCID 0000-0002-2525-749X
Jaak KalsInstitute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia ; Department of Vascular Surgery, Tartu University Hospital, 8 Puusepa Street, 51014 Tartu, Estonia.
Vahur ÖöpikInstitute of Exercise Biology and Physiotherapy, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia ; Estonian Centre of Behavioural and Health Sciences, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia.
Mihkel ZilmerInstitute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
Kersti ZilmerInstitute of Biomedicine and Translational Medicine, University of Tartu, 19 Ravila Street, 50411 Tartu, Estonia.
Jaan EhaDepartment of Cardiology, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia.
Eve UntEstonian Centre of Behavioural and Health Sciences, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia ; Department of Cardiology, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia ; Department of Sports Medicine and Rehabilitation, University of Tartu, 18 Ülikooli Street, 50090 Tartu, Estonia ; Sports Medicine and Rehabilitation Clinic, Tartu University Hospital, 1a Puusepa Street, 50406 Tartu, Estonia.
University of Tartu · EETartu University Hospital · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim was to determine the effect of heat acclimation (HA) on oxidative stress (OxS) and inflammation in resting conditions and on the response pattern of these parameters to exhausting endurance exercise.

methodsParameters of OxS and inflammation were measured in non-heat-acclimated status (NHAS) and after a 10-day HA program (i.e., in heat-acclimated status; HAS) both at baseline and after an endurance capacity (EC) test in the heat.

resultsAs a result of HA, EC increased from 88.62 ± 27.51 to 161.95 ± 47.80 minutes (P < 0.001). HA increased OxS level: total peroxide concentration rose from 219.38 ± 105.18 to 272.57 ± 133.39  μmol/L (P < 0.05) and oxidative stress index (OSI) from 14.97 ± 8.24 to 20.46 ± 11.13% (P < 0.05). In NHAS, the EC test increased OxS level: total peroxide concentration rose from 219.38 ± 105.18 to 278.51 ± 125.76  μmol/L (P < 0.001) and OSI from 14.97 ± 8.24 to 19.31 ± 9.37% (P < 0.01). However, in HAS, the EC test reduced OSI from 20.46 ± 11.13 to 16.83 ± 8.89% (P < 0.05). The value of log high-sensitive C-reactive protein increased from -0.32 ± 0.32 to -0.12 ± 0.34 mg/L (P < 0.05) in NHAS and from -0.31 ± 0.47 to 0.28 ± 0.46 mg/L (P < 0.001) in HAS.

conclusionHA increases OxS level. However, beneficial adaptive effects of HA on acute exhaustive exercise-induced changes in OxS and inflammation parameters occur in a hot environment.

Indexed as

Oxidative StressAcclimatizationAdultC-Reactive ProteinHot TemperatureHumansInflammationLipoproteins, LDLOxygenPeroxidesPhysical EnduranceYoung AdultC-Reactive ProteinLipoproteins, LDLoxidized low density lipoproteinOxygenPeroxides

Identifiers

PMID24895525
PMCPMC4034648
OpenAlexW2066154828

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.