ArticleEuropean radiology2014
MRI displays involvement of the temporalis muscle and the deep temporal artery in patients with giant cell arteritis.
Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Validity of high resolution magnetic resonance imaging in detecting giant cell arteritis: a meta-analysis.European radiology · 2022Pooled it
- Vessel wall MR imaging of central nervous system vasculitis: a systematic review.Neuroradiology · 2022Pooled it
- Quantification of Vascular Burden on Cranial Vessel Wall Magnetic Resonance Imaging and Ophthalmic Complications in Giant Cell Arteritis.ACR open rheumatology · 2026Article
- Vasculitis syndromes: large vessel vasculitides and ANCA-associated vasculitides from a neuroradiologist's perspective.Japanese journal of radiology · 2026Review
- Morphological classification of the temporalis muscle: anatomical, radiological, and surgical perspectives.Frontiers in surgery · 2026Review
- Correlation of vascular enhancement on MRI and clinical manifestations in patients with GCA.Rheumatology advances in practice · 2026Article
- Imaging Findings in Giant Cell Arteritis: Don't Turn a Blind Eye to the Obvious!AJNR. American journal of neuroradiology · 2025Review
- Combined Orbital and Cranial Vessel Wall Magnetic Resonance Imaging for the Assessment of Disease Activity in Giant Cell Arteritis.ACR open rheumatology · 2024Article
- Black-Blood Contrast in Cardiovascular MRI.Journal of magnetic resonance imaging : JMRI · 2022Review
- Article
- Giant cell arteritis and polymyalgia rheumatica: current challenges and opportunities.Nature reviews. Rheumatology · 2017Review
- 3D-black-blood 3T-MRI for the diagnosis of thoracic large vessel vasculitis: A feasibility study.European radiology · 2017Article
- Imaging in Giant Cell Arteritis.Current rheumatology reports · 2015Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess deep temporal artery and temporalis muscle involvement in patients with giant cell arteritis (GCA). MATERIAL AND
methodsNinety-nine patients who received magnetic resonance imaging (MRI) and superficial temporal artery biopsy (TAB) were included in this study. Patients with positive TAB (n = 61) were defined as GCA patients, those with negative TAB (n = 38) as the GCA-negative reference group. Contrast-enhanced T1w-images were acquired utilizing 1.5 T and 3 T MRI. Two radiologists assessed the images. Mural contrast-hyperenhancement and wall thickening of the deep temporal artery and hyperenhancement of the muscle were defined as inflammation. MRI results were correlated with jaw claudication in 70 patients.
resultsThe two observers found temporalis muscle involvement in 19.7 % (n = 12) and 21.3 % (n = 13) of GCA patients. It occurred bilaterally in 100 %. Specificities were 92/97 % and sensitivities were 20/21 %. Deep temporal artery involvement was found in 34.4 % (n = 21) and 49.2 % (n = 30) and occurred bilaterally in 80/90.5 %. Specificities were 84/95 % and sensitivities were 34/49 %. Both structures were affected simultaneously in 18/21.3 %. Jaw claudication correlated moderately with inflammation of the temporalis muscle (r = 0.31; p < 0.05) and the deep temporal artery (r = 0.38; p = 0.01).
conclusionMRI visualizes changes in the temporalis muscle and the deep temporal artery in GCA. Moderate correlation of clinical symptoms with MRI results was observed. KEY POINTS: • Approximately 20 % of GCA patients presented with temporalis muscle inflammation. • A total of 34-49 % of GCA patients presented with vasculitis of the deep temporal artery. • In approximately 20 % of GCA patients, both structures were simultaneously involved. • Involvement of both structures correlated moderately with presence of jaw claudication. • MRI is a suitable tool for the assessment of vasculitis and muscle inflammation.
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