Evidence map›Paper›PMID 24895036›Full record

ArticleEuropean radiology2014

Improvement of image quality and radiation dose of CT perfusion of the brain by means of low-tube voltage (70 KV).

Zhen-lin Li, Hang Li, Kai Zhang, Wang-jiang Li, Xian Chen, Bin Wu, Bin Song

Abstract read
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Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

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  5. [Nonlocal low-rank and sparse matrix decomposition for low-dose cerebral perfusion CT image restoration].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
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  6. [Low-dose cerebral perfusion CT image restoration using prior image constrained diffusion tensor].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhen-lin LiDepartment of Radiology, West China Hospital of Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, 610041, China.
Hang Li
Kai Zhang
Wang-jiang Li
Xian Chen
Bin Wu
Bin Song
Sichuan University · CNWest China Hospital of Sichuan University · CNSichuan Provincial Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the feasibility of 70 kV cerebral CT perfusion by comparing image quality and radiation exposure to 80 kV.

methodsThirty patients with suspected cerebral ischemia who underwent dual-source CT perfusion were divided into group A (80 kV, 150 mAs) and group B (70 kV, 150 mAs). Quantitative comparisons were used for maximum enhancement, signal-to-noise index (SNI), and values of cerebral blood flow (CBF), cerebral blood flow (CBV), mean transit time (MTT) on CBF, CBV, and MTT images, and radiation dose from these two groups. Qualitative perfusion images were assessed by two readers.

resultsMaximum enhancement for group B was higher than group A (P < 0.05). There were no significant differences between the two groups for SNI on CBF and CBV maps (P = 0.06 - 0.576), but significant differences for MTT when SNI was measured on frontal white matter and temporo-occipital white matter (P < 0.05). There were no differences among values of CBF, CBV, and MTT for both groups (P = 0.251-0.917). Mean image quality score in group B was higher than group A for CBF (P < 0.05), but no differences for CBV (P = 0.542) and MTT (P = 0.962). Radiation dose for group B decreased compared with group A.

conclusions70 kV cerebral CT perfusion reduces radiation dose without compromising image quality. KEY POINTS: • Radiation dose is a key concern with the increased using cerebral CT perfusion. Cerebral CT perfusion of 70 kV reduces radiation dose without compromising image quality. • A 70-kV protocol could be used for cerebral CT perfusion.

Indexed as

Image EnhancementAgedBrainBrain IschemiaCerebrovascular CirculationFemaleFollow-Up StudiesHumansMaleMiddle AgedPerfusion ImagingRadiation DosageRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID24895036
OpenAlexW2095460563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.