ArticleScience signaling2014
The ABA receptor PYL8 promotes lateral root growth by enhancing MYB77-dependent transcription of auxin-responsive genes.
Article in Science signaling, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
166 citing papers in PubMed.
- The bp-miR156c-BpSPL2 module positively regulates drought tolerance by mediating lateral root development and reactive oxygen species scavenging in Betula platyphylla.Plant cell reports · 2026Article
- Exogenous ABA regulates stress tolerance of Leymus chinensis via modulation of PYL‑mediated signaling and antioxidant enzymes.Plant molecular biology · 2026Article
- The ABA receptor NtPYL6 promotes flavonol biosynthesis to enhance tobacco resistance to UV-B.Plant physiology · 2026Article
- Genome-wide identification, structural characterization, and gene expression analysis of the MYB transcription factor family in faba bean (Vicia faba L.).BMC plant biology · 2026Article
- Pangenome-scale analysis of the PYL gene family reveals evolutionary conservation, regulatory diversification and salt-responsive haplotypes inFrontiers in plant science · 2026Article
- Superabsorbent polymers seed coatings modulate transcriptomic and physiological responses to drought in rapeseed.Frontiers in plant science · 2026Article
- An attapulgite-Bacillus amyloliquefaciens biocontrol agent increases growth and medicinal metabolite content in Angelica sinensis by modulating hormonal and phenylpropanoid pathways.BMC plant biology · 2025Article
- Salt Tolerance in Soybean (Plants (Basel, Switzerland) · 2025Review
- Characterization of the ABA receptor PYL gene family and identification of DoPYL1-interacting proteins in Dendrobium officinale.BMC plant biology · 2025Article
- Pan-Genome-Based Characterization of the PYL Transcription Factor Family inPlants (Basel, Switzerland) · 2025Article
- Response of hidden architects to salt stress.Planta · 2025Review
- Deciphering ABA/PYL gene family in flax: evolutionary analysis, and abiotic stress response.Plant cell reports · 2025Article
- Construction of a Membrane Yeast Two-Hybrid Library and Screening of MsPYR1-Like Interacting Proteins in Malus sieversii.Molecular biotechnology · 2025Article
- Tea polyphenol mediatedHorticulture research · 2025Article
- Article
- The Impact of Nitrogen and Phosphorus Interaction on Growth, Nutrient Absorption, and Signal Regulation in Woody Plants.Biology · 2025Article
- Genome-wide identification of pyrabactin resistance 1-like (PYL) gene family under phytohormones and drought stresses in alfalfa (Medicago sativa).BMC genomics · 2025Article
- Identification of R2R3-MYB Gene Family and Functional Analysis of Responses of S22 Subfamily to Abiotic Stresses in Dandelion (International journal of molecular sciences · 2025Article
- A chromosome-levelActa pharmaceutica Sinica. B · 2025Article
- Fine mapping ofMolecular breeding : new strategies in plant improvement · 2025Article
106 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
The phytohormone abscisic acid (ABA) regulates plant growth, development, and abiotic stress responses. ABA signaling is mediated by a group of receptors known as the PYR1/PYL/RCAR family, which includes the pyrabactin resistance 1-like protein PYL8. Under stress conditions, ABA signaling activates SnRK2 protein kinases to inhibit lateral root growth after emergence from the primary root. However, even in the case of persistent stress, lateral root growth eventually recovers from inhibition. We showed that PYL8 is required for the recovery of lateral root growth, following inhibition by ABA. PYL8 directly interacted with the transcription factors MYB77, MYB44, and MYB73. The interaction of PYL8 and MYB77 increased the binding of MYB77 to its target MBSI motif in the promoters of multiple auxin-responsive genes. Compared to wild-type seedlings, the lateral root growth of pyl8 mutant seedlings and myb77 mutant seedlings was more sensitive to inhibition by ABA. The recovery of lateral root growth was delayed in pyl8 mutant seedlings in the presence of ABA, and the defect was rescued by exposing pyl8 mutant seedlings to the auxin IAA (3-indoleacetic acid). Thus, PYL8 promotes lateral root growth independently of the core ABA-SnRK2 signaling pathway by enhancing the activities of MYB77 and its paralogs, MYB44 and MYB73, to augment auxin signaling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.