Trial reportWorld journal of surgical oncology2014
Liver resection for young patients with large hepatocellular carcinoma: a single center experience from China.
Trial report in World journal of surgical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Association Between Body Mass Index and the Prognosis and Postoperative Complications of Hepatocellular Carcinoma: A Meta-Analysis.Medicine · 2015Pooled it
- Clinical Characteristics and Prognosis of Early-Onset Hepatocellular Carcinoma: A Retrospective Cohort Study Based on Population Data.Digestive diseases and sciences · 2024Article
- Outcomes of adolescent and young patients with hepatocellular carcinoma after curative liver resection: a retrospective study.World journal of surgical oncology · 2022Article
- Article
- Transcatheter arterial chemoembolization combined with simultaneous DynaCT-guided radiofrequency ablation in the treatment of solitary large hepatocellular carcinoma.La Radiologia medica · 2019Article
- Large hepatocellular carcinoma with local remnants after transarterial chemoembolization: treatment by sorafenib combined with radiofrequency ablation or sorafenib alone.American journal of cancer research · 2019Article
- Prognostic nomogram for hepatocellular carcinoma in adolescent and young adult patients after hepatectomy.Oncotarget · 2017Article
- Decrease of RBM4 indicates poor prognosis in patients with hepatocellular carcinoma after hepatectomy.OncoTargets and therapy · 2017Article
- Surgical treatment for hepatocellular carcinoma with portal vein tumor thrombus: a novel classification.World journal of surgical oncology · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate retrospectively the clinicopathological characteristics and outcomes of young patients with large hepatocellular carcinoma after hepatectomy.
methodsFrom January 2003 to December 2012, a total of 153 patients with large hepatocellular carcinoma (HCC) who received liver resection were included in the study. The clinicopathological features were analyzed retrospectively. The perioperative data were compared between those aged <40 years (the young group) and those aged >40 years (the older group). Prognostic factors and long-term survival were evaluated.
resultsThe young group had more hepatitis B virus-related HCC than the older group (87.2% vs 66.3%, P = 0.031). In the young group, 15 patients (21.5%) were overweight (body mass index 25 to 29.9 kg/m2) or obese (body mass index ≥30 kg/m2), and 38 patients (45.8%) were overweight or obese in the older group (P = 0.032). Other clinicopathological characteristics were similar between the two groups. The perioperative data showed that the older group had more pulmonary infection after hepatectomy. Vascular invasion and high Edmondson-Steiner grade were the independent prognostic factors for long-term survival. There was no statistical difference between the young group and the older group in overall survival and disease-free survival (P = 0.109 and P = 0.087, respectively).
conclusionsLiver resection for young patients with large HCC was safe and efficacious and should be recommended.
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