Evidence map›Paper›PMID 24894439›Full record

ArticleJournal of visualized experiments : JoVE2014

A method to make a craniotomy on the ventral skull of neonate rodents.

Adrián Rodríguez-Contreras, Lingyan Shi, Bingmei M Fu

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Adrián Rodríguez-ContrerasDepartment of Biology, The City University of New York, City College; arodrig@sci.ccny.cuny.edu.
Lingyan ShiDepartment of Biomedical Engineering, The City University of New York, City College.
Bingmei M FuDepartment of Biomedical Engineering, The City University of New York, City College.
City College · USCity University of New York · US

Funding

TNC FUNCTION IN APOPTOTIC ANTIGEN DRIVEN AUTOIMMUNITYG12RR003060 · NCRR · CITY COLLEGE OF NEW YORK · PI WALLMAN, JOSHUA · 1985 to 2011
$26.1M
Cellular/Molecular Basis of Development: Research CenterG12MD007603 · NIMHD · CITY COLLEGE OF NEW YORK · PI PEZZANO, MARK · 2012 to 2017
$11.5M
Neuronal ensembles during development of tonotopic maps in the auditory systemsSC1HD068129 · NICHD · CITY COLLEGE OF NEW YORK · PI RODRIGUEZ-CONTRERAS, ADRIAN · 2010 to 2014
$1.1M
Neuronal ensembles during development of tonotopic maps in the auditory systemSC1DC015907 · NIDCD · CITY COLLEGE OF NEW YORK · PI RODRIGUEZ-CONTRERAS, ADRIAN · 2016 to 2018
$706k
NCRR NIH HHS G12 RR003060NCRR NIH HHS G12-RR003060NICHD NIH HHS SC1 HD068129NICHD NIH HHS SC1HD068129NIDCD NIH HHS SC1 DC015907NIMHD NIH HHS G12 MD007603
6 · The paper itself

Abstract

The use of a craniotomy for in vivo experiments provides an opportunity to investigate the dynamics of diverse cellular processes in the mammalian brain in adulthood and during development. Although most in vivo approaches use a craniotomy to study brain regions located on the dorsal side, brainstem regions such as the pons, located on the ventral side remain relatively understudied. The main goal of this protocol is to facilitate access to ventral brainstem structures so that they can be studied in vivo using electrophysiological and imaging methods. This approach allows study of structural changes in long-range axons, patterns of electrical activity in single and ensembles of cells, and changes in blood brain barrier permeability in neonate animals. Although this protocol has been used mostly to study the auditory brainstem in neonate rats, it can easily be adapted for studies in other rodent species such as neonate mice, adult rodents and other brainstem regions.

Indexed as

AnimalsAnimals, NewbornCraniotomyRats

Identifiers

PMID24894439
PMCPMC4122667
OpenAlexW2028435081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.