Evidence map›Paper›PMID 24894431›Full record

ReviewArchives of toxicology2014

The optical, photothermal, and facile surface chemical properties of gold and silver nanoparticles in biodiagnostics, therapy, and drug delivery.

Lauren A Austin, Megan A Mackey, Erik C Dreaden, Mostafa A El-Sayed

Abstract readReview
In one paragraph

Review in Archives of toxicology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  8. Article
  9. Review
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  16. Tube-like Gold Clusters MACS omega · 2024
    Article
  17. Review
  18. Review
  19. Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauren A AustinLaser Dynamics Laboratory, Department of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Dr. NW, Atlanta, GA, 30332-0400, USA.
Megan A Mackey
Erik C Dreaden
Mostafa A El-Sayed

Funding

Toxicity and Efficacy of Gold Nanoparticle Photothermal Therapy in CancerU01CA151802 · NCI · EMORY UNIVERSITY · PI EL-SAYED, MOSTAFA A, SHIN, DONG M · 2010 to 2014
$2.1M
LbL Nanotechnologies for Synergistic Therapy of Advanced Ovarian CarcinomaF32EB017614 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI DREADEN, ERIK CHRISTOPHER · 2013 to 2014
$102k
NCI NIH HHS 1U01CA151802-01NCI NIH HHS U01 CA151802NIBIB NIH HHS 1F32EB017614-01NIBIB NIH HHS F32 EB017614
6 · The paper itself

Abstract

Nanotechnology is a rapidly growing area of research in part due to its integration into many biomedical applications. Within nanotechnology, gold and silver nanostructures are some of the most heavily utilized nanomaterial due to their unique optical, photothermal, and facile surface chemical properties. In this review, common colloid synthesis methods and biofunctionalization strategies of gold and silver nanostructures are highlighted. Their unique properties are also discussed in terms of their use in biodiagnostic, imaging, therapeutic, and drug delivery applications. Furthermore, relevant clinical applications utilizing gold and silver nanostructures are also presented. We also provide a table with reviews covering related topics.

Indexed as

Metal NanoparticlesAnimalsDiagnostic ImagingDrug Delivery SystemsGoldHumansNanotechnologySilverGoldSilver

Identifiers

PMID24894431
PMCPMC4136654

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.