Evidence map›Paper›PMID 24894146›Full record

ReviewAnnual review of nursing research2013

ROS and RNS signaling in skeletal muscle: critical signals and therapeutic targets.

Luke P Michaelson, Colleen Iler, Christopher W Ward

Open access · greenAbstract readReview
In one paragraph

Review in Annual review of nursing research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  12. Nanoelectrochemistry in the study of single-cell signaling.Analytical and bioanalytical chemistry · 2020
    Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luke P Michaelson
Colleen Iler
Christopher W Ward

Funding

Interdisciplinary Training Program Muscle BiologyT32AR007592 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Aikaterini Kontrogianni-Konstantopoulos · 1996 to 2026
$11.7M
Stress Induced Ca2+ Dysregulation in MDX Mouse Skeletal Muscle FibersF31NR011245 · NINR · UNIVERSITY OF MARYLAND BALTIMORE · PI MICHAELSON, LUKE PHILIP · 2009 to 2011
$84k
NIAMS NIH HHS L40 AR056534NIAMS NIH HHS T32 AR007592NINR NIH HHS F31 NR011245
6 · The paper itself

Abstract

The health of skeletal muscle is promoted by optimal nutrition and activity/exercise through the activation of molecular signaling pathways. Reactive oxygen species (ROS) or reactive nitrogen species (RNS) have been shown to modulate numerous biochemical processes including glucose uptake, gene expression, calcium signaling, and contractility. In pathological conditions, ROS/RNS signaling excess or dysfunction contributes to contractile dysfunction and myopathy in skeletal muscle. Here we provide a brief review of ROS/RNS chemistry and discuss concepts of ROS/RNS signaling and its role in physiological and pathophysiological processes within striated muscle.

Indexed as

Signal TransductionHumansMuscle, SkeletalReactive Nitrogen SpeciesReactive Oxygen SpeciesReactive Nitrogen SpeciesReactive Oxygen Species

Identifiers

PMID24894146
PMCPMC4942739
OpenAlexW2322247690

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.