Evidence map›Paper›PMID 24894077›Full record

Trial reportBMC pediatrics2014

Gut-directed hypnotherapy in children with irritable bowel syndrome or functional abdominal pain (syndrome): a randomized controlled trial on self exercises at home using CD versus individual therapy by qualified therapists.

Juliette M T M Rutten, Arine M Vlieger, Carla Frankenhuis, Elvira K George, Michael Groeneweg, Obbe F Norbruis, Walther Tjon a Ten, Herbert Van Wering, Marcel G W Dijkgraaf, Maruschka P Merkus and 1 more

2 registry-linked trialsOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03884270 nacompletednot on this mapstarted 2019, after this paper: background citation

Self-Administered Hypnotherapy for Functional Dyspepsia

TypeinterventionalSponsorSarah KinsingerRan2019 to 2020Enrolled23ConditionsFunctional DyspepsiaArmsHypnotherapy
NCT05636358 nacompletednot on this mapstarted 2021, after this paper: background citation

Hypnotherapy Through Self-exercises in Children With Functional Abdominal Pain in Primary Care

TypeinterventionalSponsorUniversity Medical Center GroningenRan2021 to 2024Enrolled152ConditionsFunctional Gastrointestinal Disorders, Irritable Bowel Syndrome, Functional Abdominal Pain SyndromeArmsHome-based hypnotherapy
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. The Efficacy, Safety and Applications of Medical Hypnosis.Deutsches Arzteblatt international · 2016
    Pooled it
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  15. Brain-Gut Axis: Clinical Implications.Gastroenterology clinics of North America · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Juliette M T M RuttenDepartment of Pediatric Gastroenterology, Emma Children's Hospital/Academic Medical Center, PO Box 22700, 1100 DD Amsterdam, The Netherlands. j.m.rutten@amc.nl.
Arine M Vlieger
Carla Frankenhuis
Elvira K George
Michael Groeneweg
Obbe F Norbruis
Walther Tjon a Ten
Herbert Van Wering
Marcel G W Dijkgraaf
Maruschka P Merkus
Marc A Benninga
Emma Kinderziekenhuis · NLUniversity of Amsterdam · NLAcademic Medical Center · NLAmphia Ziekenhuis · NLIsala · NLMaasstad Ziekenhuis · NLMáxima Medisch Centrum · NLMedisch Centrum Alkmaar · NLSt. Antonius Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIrritable bowel syndrome (IBS) and functional abdominal pain (syndrome) (FAP(S)) are common pediatric disorders, characterized by chronic or recurrent abdominal pain. Treatment is challenging, especially in children with persisting symptoms. Gut-directed hypnotherapy (HT) performed by a therapist has been shown to be effective in these children, but is still unavailable to many children due to costs, a lack of qualified child-hypnotherapists and because it requires a significant investment of time by child and parent(s). Home-based hypnotherapy by means of exercises on CD has been shown effective as well, and has potential benefits, such as lower costs and less time investment. The aim of this randomized controlled trial (RCT) is to compare cost-effectiveness of individual HT performed by a qualified therapist with HT by means of CD recorded self-exercises at home in children with IBS or FAP(S). METHODS/

design260 children, aged 8-18 years with IBS or FAP(S) according to Rome III criteria are included in this currently conducted RCT with a follow-up period of one year. Children are randomized to either 6 sessions of individual HT given by a qualified therapist over a 3-month period or HT through self-exercises at home with CD for 3 months.The primary outcome is the proportion of patients in which treatment is successful at the end of treatment and after one year follow-up. Treatment success is defined as at least 50% reduction in both abdominal pain frequency and intensity scores. Secondary outcomes include adequate relief, cost-effectiveness and effects of both therapies on depression and anxiety scores, somatization scores, QoL, pain beliefs and coping strategies. DISCUSSION: If the effectiveness of home-based HT with CD is comparable to, or only slightly lower, than HT by a therapist, this treatment may become an attractive form of therapy in children with IBS or FAP(S), because of its low costs and direct availability.

trial registrationDutch Trial Register number NTR2725 (date of registration: 1 February 2011).

Indexed as

Abdominal PainAdaptation, PsychologicalAdolescentAnxietyChildCost-Benefit AnalysisHumansHypnosisIrritable Bowel SyndromeNetherlandsSelf CareStress, PsychologicalSurveys and Questionnaires

Identifiers

PMID24894077
PMCPMC4060754
OpenAlexW2089839909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.