ArticleThe Plant cell2014
A Role for CHH Methylation in the Parent-of-Origin Effect on Altered Circadian Rhythms and Biomass Heterosis in Arabidopsis Intraspecific Hybrids.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 74 citations in OpenAlex.
- Response of DNA methylation and gene expression to light treatments in Norway spruce [Picea abies (L.) Karst.].BMC genomics · 2026Article
- DNA Methylation Dynamics in Plant Abiotic Stress Response: Mechanisms, Memory, and Breeding Applications.Genes · 2026Review
- 24-nt-phasiRNA associated CHG/CHH DNA methylation contributes to growth heterosis ofForestry research · 2026Article
- Integrating Multi-omics Analysis to Decipher the Genetic Basis of Heterosis in Xieyou9308.Rice (New York, N.Y.) · 2025Article
- DNA methylation in plant heterosis: mechanisms and prospects.Functional & integrative genomics · 2025Review
- Photoperiod and Circadian Regulation in Plants: A Review of Insights from In Vitro Studies.Biology · 2025Review
- Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025Review
- Transcriptome and DNA methylation analyses provide insight into the heterosis of growth-related traits in hybrid yellow croaker.BMC genomics · 2025Article
- Parent-of-origin effects orchestrate transcriptional reprogramming and epigenetic regulation of seedling vigor heterosis in triploid loquat.Frontiers in plant science · 2025Article
- Transgenerational epigenetic inheritance during plant evolution and breeding.Trends in plant science · 2024Review
- Imprinting but not cytonuclear interactions determines seed size heterosis in Arabidopsis hybrids.Plant physiology · 2024Article
- Circadian and photoperiodic regulation of the vegetative to reproductive transition in plants.Communications biology · 2024Review
- Unlocking allelic variation in circadian clock genes to develop environmentally robust and productive crops.Planta · 2024Review
- Comparative transcriptomic analysis reveals the molecular mechanism underlying seedling heterosis and its relationship with hybrid contemporary seeds DNA methylation in soybean.Frontiers in plant science · 2024Article
- Unveiling the imprinted dance: how parental genomes orchestrate seed development and hybrid success.Frontiers in plant science · 2024Review
- Characteristics ofHorticulture research · 2023Article
- Protein nonadditive expression and solubility contribute to heterosis inFrontiers in plant science · 2023Article
- Gene expression variations and allele-specific expression of two rice and their hybrid in caryopses at single-nucleus resolution.Frontiers in plant science · 2023Article
- Heterosis and Differential DNA Methylation in Soybean Hybrids and Their Parental Lines.Plants (Basel, Switzerland) · 2022Article
- Small RNAs mediate transgenerational inheritance of genome-wide trans-acting epialleles in maize.Genome biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hybrid plants and animals often show increased levels of growth and fitness, a phenomenon known as hybrid vigor or heterosis. Circadian rhythms optimize physiology and metabolism in plants and animals. In plant hybrids and polyploids, expression changes of the genes within the circadian regulatory network, such as CIRCADIAN CLOCK ASSOCIATED1 (CCA1), lead to heterosis. However, the relationship between allelic CCA1 expression and heterosis has remained elusive. Here, we show a parent-of-origin effect on altered circadian rhythms and heterosis in Arabidopsis thaliana F1 hybrids. This parent-of-origin effect on biomass heterosis correlates with altered CCA1 expression amplitudes, which are associated with methylation levels of CHH (where H = A, T, or C) sites in the promoter region. The direction of rhythmic expression and hybrid vigor is reversed in reciprocal F1 crosses involving mutants that are defective in the RNA-directed DNA methylation pathway (argonaute4 and nuclear RNA polymerase D1a) but not in the maintenance methylation pathway (methyltransferase1 and decrease in DNA methylation1). This parent-of-origin effect on circadian regulation and heterosis is established during early embryogenesis and maintained throughout growth and development.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.