Evidence map›Paper›PMID 24894026›Full record

Trial reportIntensive care medicine2014

A randomized clinical trial of an intervention to relieve thirst and dry mouth in intensive care unit patients.

Kathleen Puntillo, Shoshana R Arai, Bruce A Cooper, Nancy A Stotts, Judith E Nelson

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03215251 nacompletednot on this mapstarted 2015, after this paper: background citation

Experimental Study to Evaluate the Effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth Among Patients of Selected Units

TypeinterventionalSponsorMaharishi Markendeswar University (Deemed to be University)Ran2015 to 2017Enrolled60ConditionsThirst, Dry MouthArmsIntervention bundle
NCT06463158 narecruitingnot on this mapstarted 2024, after this paper: background citation

A Phase I Clinical Trial Evaluating the Impact of the Family Room App on Caregiver Well-being, Satisfaction, and Engagement in the Intensive Care Unit

TypeinterventionalSponsorUniversity of NebraskaRan2024 to 2027Enrolled100ConditionsWell-Being, Psychological, Engagement, Satisfaction, ConsumerArmsFamily Room Application
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it, 141 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kathleen PuntilloDepartment of Physiological Nursing, University of California, San Francisco, San Francisco, CA, USA, Kathleen.puntillo@nursing.ucsf.edu.
Shoshana R Arai
Bruce A Cooper
Nancy A Stotts
Judith E Nelson
University of California, San Francisco · USIcahn School of Medicine at Mount Sinai · US

Funding

Palliation of Thirst in Intensive Care Unit PatientsR01NR011825 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PUNTILLO, KATHLEEN A · 2009 to 2011
$1.3M
Informing/Improving ICU Palliative Care for Older AdultsK07AG034234 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NELSON, JUDITH E · 2009 to 2013
$540k
NIA NIH HHS AG034234NIA NIH HHS K07 AG034234NINR NIH HHS 1NR011825-03NINR NIH HHS R01 NR011825
6 · The paper itself

Abstract

purposeTo test an intervention bundle for thirst intensity, thirst distress, and dry mouth, which are among the most pervasive, intense, distressful, unrecognized, and undertreated symptoms in ICU patients, but for which data-based interventions are lacking.

methodsThis was a single-blinded randomized clinical trial in three ICUs in a tertiary medical center in urban California. A total of 252 cognitively intact patients reporting thirst intensity (TI) and/or thirst distress (TD) scores ≥3 on 0-10 numeric rating scales (NRS) were randomized to intervention or usual care groups. A research team nurse (RTN#1) obtained patients' pre-procedure TI and TD scores and reports of dry mouth. She then administered a thirst bundle to the intervention group: oral swab wipes, sterile ice-cold water sprays, and a lip moisturizer, or observed patients in the usual care group. RTN#2, blinded to group assignment, obtained post-procedure TI and TD scores. Up to six sessions per patient were conducted across 2 days.

resultsMultilevel linear regression determined that the average decreases in TI and TD scores from pre-procedure to post-procedure were significantly greater in the intervention group (2.3 and 1.8 NRS points, respectively) versus the usual care group (0.6 and 0.4 points, respectively) (p < 0.05). The usual care group was 1.9 times more likely than the intervention group to report dry mouth for each additional session on day 1.

conclusionThis simple, inexpensive thirst bundle significantly decreased ICU patients' thirst and dry mouth and can be considered a practice intervention for patients experiencing thirst.

Indexed as

Critical CareThirstFemaleHumansIntensive Care UnitsLongitudinal StudiesMaleMiddle AgedSingle-Blind MethodXerostomia

Identifiers

PMID24894026
PMCPMC4149585
OpenAlexW1980224044

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.