Evidence map›Paper›PMID 24893160›Full record

ArticlePloS one2014

From transmission to transition: lessons learnt from the Thai paediatric antiretroviral programme.

Olivia Tulloch, Sally Theobald, Jintanat Ananworanich, Sanchai Chasombat, Pope Kosalaraksa, Thidaporn Jirawattanapisal, Sudrak Lakonphon, Pagakrong Lumbiganon, Miriam Taegtmeyer

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Mental health challenges among adolescents living with HIV.Journal of the International AIDS Society · 2017
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Getting to 90-90-90 in paediatric HIV: What is needed?Journal of the International AIDS Society · 2015
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Olivia TullochDepartment of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Sally TheobaldDepartment of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Jintanat AnanworanichSEARCH and HIV-NAT, The Thai Red Cross AIDS Research Center, Bangkok, Thailand; Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Sanchai ChasombatBureau of AIDS, Tuberculosis and Sexually Transmitted Infections, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Pope KosalaraksaDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Thidaporn JirawattanapisalBureau of AIDS, Tuberculosis and Sexually Transmitted Infections, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Sudrak LakonphonSEARCH and HIV-NAT, The Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Pagakrong LumbiganonDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Miriam TaegtmeyerDepartment of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Liverpool School of Tropical Medicine · GBDepartment of Disease Control · THKhon Kaen University · THChulalongkorn University · THHIV Netherlands Australia Thailand Research Collaboration · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Thai HIV programme is a leader in the public health approach to HIV treatment. Starting at transmission of HIV and ending with transition to adult services this paper assesses the paediatric HIV treatment continuum from three perspectives: service-user, provider and policy maker, to understand what works well and why.

methodsA qualitative research design was used to assess and triangulate the stakeholder perspectives. Semi-structured interviews were conducted with ART service-users (n = 35), policy actors (n = 20); telephone interviews with prior caregivers of orphans (n = 10); and three focus group discussions with service-providers (hospital staff and volunteers) from a district, provincial and a university hospital.

findingsChildren accessing HIV care were often orphaned, cared for by elderly relatives and experiencing multiple vulnerabilities. Services were divided into three stages, 1. Diagnosis and linkage: Despite strong policies there were supply and demand-side gaps in the prevention of mother-to-child transmission 'cascade' preventing early diagnosis and/or treatment. 2. Maintenance on ART - Children did well on treatment; caregivers took adherence seriously and valued the quality of services. Drug resistance, adherence and psychosocial issues were important concerns from all perspectives. 3. Adolescents and transition: Adolescent service-users faced greater complexity in their physical and emotional lives for which providers lacked skills; transition from the security of paediatric clinic was a daunting prospect. Dedicated healthcare providers felt they struggled to deliver services that met service-users' diverse needs at all stages. Child- and adolescent-specific elements of HIV policy were considered low priority.

conclusionsUsing the notion of the continuum of care a number of strengths and weaknesses were identified. Features of paediatric services need to evolve alongside the changing needs of service users. Peer-support volunteers have potential to add continuity and support at all stages. It is critical that adolescents receive targeted support, particularly during transition to adult services.

Indexed as

Delivery of Health CareAdolescentAdultAnti-Retroviral AgentsCaregiversChildChild, OrphanedHIV InfectionsHumansInterviews as TopicProgram EvaluationPsychology, AdolescentThailandAnti-Retroviral Agents

Identifiers

PMID24893160
PMCPMC4043947
OpenAlexW2120727039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.