ArticlePloS one2014
Interaction of obesity and central obesity on elevated urinary albumin-to-creatinine ratio.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- A study on the construction of body fat percentage percentile curve for adults aged 20-79 in China.Frontiers in public health · 2025Article
- Rediscovery of the implication of albuminuria in heart failure: emerging classic index for cardiorenal interaction.ESC heart failure · 2024Review
- Impact of Obesity in Kidney Diseases.Nutrients · 2021Review
- Article
- Association Between Hearing Impairment and Albuminuria With or Without Diabetes Mellitus.Clinical and experimental otorhinolaryngology · 2017Article
- Article
- The kidney in obesity.Current hypertension reports · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroalbuminuria was much more common among obese individuals indicating a probable association with obesity. However, association of microalbuminuria with interaction between obesity and central obesity has not yet been studied. DESIGN AND
methodsA cross-sectional study was conducted in a 2889 general population aged ≥ 30 years. Obesity was defined as body mass index ≥ 28.0 kg/m2 and central obesity was defined as waist-to-hip ratio ≥ 0.85 for females and ≥ 0.90 for males. Both additive and multipliable interactions between obesity and central obesity on elevated urinary albumin-to-creatinine ratio (UACR) were evaluated.
resultsAfter controlling for potential covariates, participants with both obesity and central obesity have significantly increased risk for elevated UACR (OR = 1.82 P<0.001) compared to those with neither. Additive interaction analysis indicated that about 43.9% of the risk of elevated UACR in participants with both obesity and central obesity was attributed to the interaction between obesity and central obesity (the attributable proportion because of the interaction: 0.439; 95% CI: 0.110-0.768). The multipliable interactive effect between obesity and central obesity on elevated UACR was not found significant (OR = 1.82, P = 0.078).
conclusionsMicroalbuminuria was significantly associated with the interaction between obesity and central obesity. Our results indicated that individuals with both obesity and central obesity should be intensively managed to prevent renal diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.