Evidence map›Paper›PMID 24892912›Full record

ArticleCurrent biology : CB2014

Bacterial evolution: rewiring modules to get in shape.

Alexandre Persat, Zemer Gitai

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Alexandre PersatDepartment of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Room 355, Princeton, NJ 08544, USA.
Zemer GitaiDepartment of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Room 355, Princeton, NJ 08544, USA. Electronic address: zgitai@princeton.edu.

Funding

Discovering Antibiotic Drugs & Targets via High-Throughput Bacterial Cell BiologyDP2OD004389 · OD · PRINCETON UNIVERSITY · PI GITAI, ZEMER · 2008 to 2008
$2.4M
Caulobacter cell shape and cytoskeletal regulationR01GM107384 · NIGMS · PRINCETON UNIVERSITY · PI GITAI, ZEMER · 2013 to 2016
$1.5M
NIGMS NIH HHS R01 GM107384NIH HHS DP2 OD004389
6 · The paper itself

Abstract

Bacterial species take on a wide variety of shapes, but the mechanisms by which specific shapes evolve have remained poorly understood. A recent study demonstrates that two Asticcacaulis species repurposed an ancestral regulatory protein to rewire the modules of stalk regulation, localization, and synthesis, thereby generating new shapes.

Indexed as

Biological EvolutionCell PolarityBacteriaBacterial ProteinsBacterial Proteins

Identifiers

PMID24892912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.