Evidence map›Paper›PMID 24892770›Full record

SynthesisJAMA2014

Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality.

Josef Coresh, Tanvir Chowdhury Turin, Kunihiro Matsushita, Yingying Sang, Shoshana H Ballew, Lawrence J Appel, Hisatomi Arima, Steven J Chadban, Massimo Cirillo, Ognjenka Djurdjev and 17 more

2 registry-linked trialsOpen access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in JAMA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 568 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
568citing papers in PubMed, 9 pooled it
44.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01194518 nacompletednot on this map

Exploring Life Experience and Lifestyle Intervention Program Among Patients With Chronic Kidney Disease: A Longitudinal Study

TypeinterventionalSponsorNational Cheng Kung UniversityRan2010 to 2013Enrolled120ConditionsChronic Kidney Diseases, Health Behaviors, Patient EducationArmsLifestyle counseling Program
NCT05189418 completednot on this mapstarted 2022, after this paper: background citation

Sleep-time Blood Pressure Determined by Home and Ambulatory Monitoring as Potential Prognostic Factor for Chronic Kidney Disease (CKD) Progression, Mortality, and Cardiovascular Morbidity in Patients With Advanced CKD

Typeobservational_patient_registrySponsorUniversity of VigoRan2022 to 2024Enrolled210ConditionsChronic Kidney DiseasesArmsAmbulatory blood pressure monitoring (ABPM), Home blood pressure monitoring (HBPM)
3 · Its place in the literature

Who cites it

568 citing papers in PubMed, 9 syntheses or guidelines pooled it, 964 citations in OpenAlex.

  1. Pooled it
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  6. Clonal Hematopoiesis of Indeterminate Potential and Kidney Function Decline in the General Population.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
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  15. Time in target range of systolic blood pressure and eGFR slope in patients with type 2 diabetes.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Trial
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  19. Rates of Reversal of Volume Overload in Hospitalized Acute Heart Failure: Association With Long-term Kidney Function.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Trial
  20. Article

508 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors at 19 institutions in 11 countries.

Josef Coresh *Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Tanvir Chowdhury Turin *Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Kunihiro MatsushitaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Yingying SangJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Shoshana H BallewJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Lawrence J AppelJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Hisatomi ArimaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Steven J ChadbanJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Massimo CirilloJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Ognjenka DjurdjevJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Jamie A GreenJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Gunnar H HeineJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Lesley A InkerJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Fujiko IrieJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Areef IshaniJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Joachim H IxJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Csaba P KovesdyJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Angharad MarksJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Takayoshi OhkuboJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Varda ShalevJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Anoop ShankarJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Chi Pang WenJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Paul E de JongJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Kunitoshi IsekiJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Benedicte StengelJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Ron T Gansevoort *Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Andrew S Levey *Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA (J Coresh, K Matsushita, Y Sang, SH Ballew); Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada (TC Turin); Johns Hopkins Medical Institutions, Baltimore, MD, 21205 (LJ Appel); The George Institute for Global Health, University of Sydney, Sydney, NSW, Australia (H Arima); Department of Nephrology and Transplantation, Royal Prince Alfred Hospital, Sydney, NSW, Australia and Sydney Medical School, University of Sydney, Sydney, NSW, Australia (SJ Chadban); Department of Medicine, University of Salerno, Salerno, Italy (M Cirillo); BC Provincial Renal Agency, Vancouver, Canada (O Djurdjev); Nephrology Department, Geisinger Medical Center, Danville, PA, USA (JA Green); Department of Internal Medicine IV-Nephrology and Hypertension, Saarland University Medical Center, D-66421 Homburg, Germany (GH Heine); Division of Nephrology at Tufts Medical Center, Boston, MA 02111, USA (LA Inker, AS Levey); Department of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan (F Irie); Minneapolis VA Health Care System and Department of Medicine, University of Minnesota, Minneapolis, MN, USA (A Ishani); University of California San Diego, San Diego, CA, USA (JH Ix); Memphis Veterans Affairs Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA (CP Kovesdy); Division of Applied Health Sciences, University of Aberdeen, and NHS Grampian, Foresterhill, Aberdeen, UK (A Marks); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan, Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, Japan, and Department of Health Science, Shiga University of Medical Science, Setatuskinowa, Otsu, Japan (T Ohkubo); Medical Informatics Department, Maccabi Healthcare Services, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (V Shalev); Department of Family Medicine and Population Health, Virginia Commonwealth University, School of Medicine, 830 E. Main Street, P.O. Box 980212, Richmond, VA 23298-0212 (A Shankar); China Medical University Hospital, Taichung, Taiwan and Institute of Population Health Science, National Health Research Institutes, Zhunan, Taiwan (CP Wen); Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands (PE de Jong, RT Gansevoort); Dialysis Unit, University Hospital of The Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan (K Iseki); Inserm U1018, CESP Center for Research in Epidemiology and Population Health, Villejuif, France and UMRS 1018, Paris-Sud University, Villejuif, France (B Stengel).
Johns Hopkins University · USTufts Medical Center · USUniversity Medical Center Groningen · NLUniversity of Sydney · AUCentre de recherche en Epidémiologie et Santé des Populations · FRChina Medical University Hospital · TWGeisinger Medical Center · USIbaraki Prefectural Police · JPMemphis VA Medical Center · USNHS Grampian · GBTel Aviv University · ILTohoku University · JPUniversität Hamburg · DEUniversity of Calgary · CAUniversity of California, San Diego · USUniversity of Minnesota · USUniversity of Salerno · ITUniversity of the Ryukyus · JPVirginia Commonwealth University · US

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
Chronic Kidney Disease Prognosis Consortium (CKD-PC)R01DK100446 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, Morgan Erika Grams · 2014 to 2026
$10.7M
Exceptional Survival: Trajectories to Functional Aging (CHS All Stars)R01AG023629 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEWMAN, ANNE B. · 2004 to 2016
$9.5M
CHS Events Follow-up StudyR01HL080295 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M · 2009 to 2014
$6.3M
MORTALITY FOLLOW-UP AND ANALYSES OF MEN IN THE MRFITR01HL068140 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI NEATON, JAMES DENNIS · 2001 to 2005
$2.6M
Role of EIIIA fibronectin in pulmonary fibrosisR01HL085083 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WHITE, ERIC S · 2007 to 2011
$1.9M
GENDER DIFFERENCES IN OSTEOPOROSISR01AG007181 · NIA · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1999 to 2002
$1.6M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
CVD Predictors of Cognitive Function Trajectory over 20 YearsR01AG028507 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 2007 to 2010
$1.2M
Novel Cardiac Risk Factors &Endothelial Function in CKDK23DK067303 · NIDDK · TUFTS MEDICAL CENTER · PI MENON, VANDANA · 2004 to 2008
$781k
Chief Scientist Office CZH/4/656Medical Research Council MC_PC_13040Medical Research Council MR/K007017/1NCATS NIH HHS UL1 TR001079NCRR NIH HHS UL1 RR024156NCRR NIH HHS UL1 RR025005NHLBI NIH HHS HHSN268200800007CNHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS HHSN268201200036CNHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01 HC055222NHLBI NIH HHS N01 HC085079NHLBI NIH HHS N01 HC085080NHLBI NIH HHS N01 HC085081NHLBI NIH HHS N01 HC085082NHLBI NIH HHS N01 HC085083NHLBI NIH HHS N01 HC085086NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL043232NHLBI NIH HHS R01 HL068140NHLBI NIH HHS R01 HL080295NIA NIH HHS R01 AG007181NIA NIH HHS R01 AG023629NIA NIH HHS R01 AG028507NIDDK NIH HHS K23 DK002904NIDDK NIH HHS K23 DK067303NIDDK NIH HHS R01 DK031801NIDDK NIH HHS R01 DK100446NIDDK NIH HHS R01DK100446NIDDK NIH HHS U01 DK035073
6 · The paper itself

Abstract

importanceThe established chronic kidney disease (CKD) progression end point of end-stage renal disease (ESRD) or a doubling of serum creatinine concentration (corresponding to a change in estimated glomerular filtration rate [GFR] of −57% or greater) is a late event.

objectiveTo characterize the association of decline in estimated GFR with subsequent progression to ESRD with implications for using lesser declines in estimated GFR as potential alternative end points for CKD progression. Because most people with CKD die before reaching ESRD, mortality risk also was investigated. DATA SOURCES AND STUDY SELECTION: Individual meta-analysis of 1.7 million participants with 12,344 ESRD events and 223,944 deaths from 35 cohorts in the CKD Prognosis Consortium with a repeated measure of serum creatinine concentration over 1 to 3 years and outcome data. DATA EXTRACTION AND SYNTHESIS: Transfer of individual participant data or standardized analysis of outputs for random-effects meta-analysis conducted between July 2012 and September 2013, with baseline estimated GFR values collected from 1975 through 2012. MAIN OUTCOMES AND MEASURES: End-stage renal disease (initiation of dialysis or transplantation) or all-cause mortality risk related to percentage change in estimated GFR over 2 years, adjusted for potential confounders and first estimated GFR.

resultsThe adjusted hazard ratios (HRs) of ESRD and mortality were higher with larger estimated GFR decline. Among participants with baseline estimated GFR of less than 60 mL/min/1.73 m2, the adjusted HRs for ESRD were 32.1 (95% CI, 22.3-46.3) for changes of −57% in estimated GFR and 5.4 (95% CI, 4.5-6.4) for changes of −30%. However, changes of −30% or greater (6.9% [95% CI, 6.4%-7.4%] of the entire consortium) were more common than changes of −57% (0.79% [95% CI, 0.52%-1.06%]). This association was strong and consistent across the length of the baseline period (1 to 3 years), baseline estimated GFR, age, diabetes status, or albuminuria. Average adjusted 10-year risk of ESRD (in patients with a baseline estimated GFR of 35 mL/min/1.73 m2) was 99% (95% CI, 95%-100%) for estimated GFR change of −57%, was 83% (95% CI, 71%-93%) for estimated GFR change of −40%, and was 64% (95% CI, 52%-77%) for estimated GFR change of −30% vs 18% (95% CI, 15%-22%) for estimated GFR change of 0%. Corresponding mortality risks were 77% (95% CI, 71%-82%), 60% (95% CI, 56%-63%), and 50% (95% CI, 47%-52%) vs 32% (95% CI, 31%-33%), showing a similar but weaker pattern. CONCLUSIONS AND RELEVANCE: Declines in estimated GFR smaller than a doubling of serum creatinine concentration occurred more commonly and were strongly and consistently associated with the risk of ESRD and mortality, supporting consideration of lesser declines in estimated GFR (such as a 30% reduction over 2 years) as an alternative end point for CKD progression.

Indexed as

Glomerular Filtration RateAdultAgedAged, 80 and overCohort StudiesCreatinineDisease ProgressionEndpoint DeterminationFemaleHumansKidney Failure, ChronicMaleMiddle AgedReference ValuesRiskCreatinine

Identifiers

PMID24892770
PMCPMC4172342
OpenAlexW1981055539

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.