Evidence map›Paper›PMID 24892524›Full record

ArticleSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2014

Hydroxyapatite grafted carbon nanotubes and graphene nanosheets: promising bone implant materials.

Adebola Oyefusi, Opeyemi Olanipekun, Gururaj M Neelgund, Deforest Peterson, Julia M Stone, Ebonee Williams, Laura Carson, Gloria Regisford, Aderemi Oki

Abstract read
In one paragraph

Article in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
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  6. Effect of TiONanomaterials (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Adebola OyefusiDepartment of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States.
Opeyemi OlanipekunDepartment of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States.
Gururaj M NeelgundDepartment of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States.
Deforest PetersonCooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.
Julia M StoneCooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.
Ebonee WilliamsCooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.
Laura CarsonCooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.
Gloria RegisfordDepartment of Biology, Prairie View A&M University, Prairie View, TX 77446, United States.
Aderemi OkiDepartment of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States. Electronic address: aroki@pvamu.edu.
Prairie View A&M University · US

Funding

Graphene Based Nanocomposites for Bone Tissue EngineeringSC3GM121229 · NIGMS · PRAIRIE VIEW AGRI & MECH UNIVERSITY · PI OKI, ADEREMI R · 2017 to 2020
$447k
Hybrid Organic-Inorganic Composite Materials for Bone RepairsSC3GM086245 · NIGMS · PRAIRIE VIEW AGRI & MECH UNIVERSITY · PI OKI, ADEREMI R · 2009 to 2012
$428k
NIGMS NIH HHS 1SC3GM086245NIGMS NIH HHS SC3 GM086245NIGMS NIH HHS SC3 GM121229
6 · The paper itself

Abstract

In the present study, hydroxyapatite (HA) was successfully grafted to carboxylated carbon nanotubes (CNTs) and graphene nanosheets. The HA grafted CNTs and HA-graphene nanosheets were characterized using FT-IR, TGA, SEM and X-ray diffraction. The HA grafted CNTs and graphene nanosheets (CNTs-HA and Gr-HA) were further used to examine the proliferation and differentiation rate of temperature-sensitive human fetal osteoblastic cell line (hFOB 1.19). Total protein assays and western blot analysis of osteocalcin expression were used as indicators of cell proliferation and differentiation. Results indicated that hFOB 1.19 cells proliferate and differentiate well in treatment media containing CNTs-HA and graphene-HA. Both CNTs-HA and graphene-HA could be promising nanomaterials for use as scaffolds in bone tissue engineering.

Indexed as

Prostheses and ImplantsBlotting, WesternBone and BonesCell LineDurapatiteFetusGraphiteHumansNanoparticlesNanotubes, CarbonOsteoblastsOsteocalcinPowdersSpectroscopy, Fourier Transform InfraredTemperatureThermogravimetryDurapatiteGraphiteNanotubes, CarbonOsteocalcinPowdersBioceramicCarbon nanotubesGraphenehFOB 1.19 cellsHydroxyapatite

Identifiers

PMID24892524
PMCPMC4096586
OpenAlexW2005113048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.