ArticleTheScientificWorldJournal2014
Alteration of cytokine profiles in uranium miners exposed to long-term low dose ionizing radiation.
Article in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Radon exposure and potential health effects other than lung cancer: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Extracellular vesicle proteomic expression is influenced by mining tenure in former uranium miners.Environmental research · 2025Article
- Low-Dose Ionizing Radiation and Male Reproductive Immunity: Elucidating Subtle Modulations and Long-Term Health Implications.International journal of molecular sciences · 2025Review
- Comprehensive computational analysis via Adverse Outcome Pathways and Aggregate Exposure Pathways in exploring synergistic effects from radon and tobacco smoke on lung cancer.Frontiers in public health · 2025Article
- Serum Level Alteration of IL-6, IL-1TheScientificWorldJournal · 2024Article
- DNA methylome profiling in occupational radon exposure miners using an Illumina Infinium Methylation EPIC BeadChip.Toxicology research · 2023Article
- Environmental uranium exposures and cytokine profiles among mother-newborn baby pairs from the Navajo Βirth Cohort Study.Toxicology and applied pharmacology · 2022Article
- The immunotoxicity of natural and depleted uranium: From cells to people.Toxicology and applied pharmacology · 2022Review
- Same pollution sources for climate change might be hyperactivating the NLRP3 inflammasome and exacerbating neuroinflammation and SARS mortality.Medical hypotheses · 2021Review
- Inflammatory profile dysregulation in nuclear workers occupationally exposed to low-dose gamma radiation.Journal of radiation research · 2019Article
- Dose-Response Effects of Low-Dose Ionizing Radiation on Blood Parameters in Industrial Irradiation Workers.Dose-response : a publication of International Hormesis SocietyArticle
- Analysis of Red Blood Cells and their Components in Medical Workers with Occupational Exposure to Low-Dose Ionizing Radiation.Dose-response : a publication of International Hormesis SocietyArticle
- Plasma Proteins As Biodosimetric Markers of Low-Dose Radiation in Mice.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study is to estimate the immune function through cytokine profiles in sera of uranium mines.
methodsAntibody arrays were used to detect 50 cytokines in sera of uranium miners. Miners who had continuously worked underground for <5 years were treated as control group and those who worked for ⩾ 5 years as experimental group.
resultsOf 28 measurable cytokines, the release of IL-1 α , IL-1RI, IL-15, IL-3, and IP-10 were significantly upregulated in the experimental group, and no cytokine was found significantly downregulated. Other proinflammatory cytokines such as IFN-γ, IL-10, IL-6, and TNF α levels were slightly upregulated in the experimental group. With adjustment to age, BMI, and cigarette smoking, IL-1 α and IL-3 levels increased significantly with underground time.
conclusionAlteration of cytokine profiles in this study may indicate persistent inflammatory responses in uranium miners exposed to long-term low doses radiation.
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Registered trials
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