ReviewWorld journal of gastrointestinal pathophysiology2014
Microscopic colitis: Common cause of unexplained nonbloody diarrhea.
Review in World journal of gastrointestinal pathophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Evaluation of Melatonin Secretion and Metabolism Exponents in Patients with Ulcerative and Lymphocytic Colitis.Molecules (Basel, Switzerland) · 2018Trial
- Article
- Microscopic Colitis: Pathogenesis and Diagnosis.Journal of clinical medicine · 2023Review
- Enteric Viruses Nucleic Acids Distribution along the Digestive Tract of Rhesus Macaques with Idiopathic Chronic Diarrhea.Viruses · 2022Article
- Idiopathic Chronic Diarrhea in Rhesus Macaques Is Not Associated with Enteric Viral Infections.Viruses · 2021Article
- Comparative transcriptome and microbiota analyses provide new insights into the adverse effects of industrial trans fatty acids on the small intestine of C57BL/6 mice.European journal of nutrition · 2021Article
- Management of microscopic colitis: challenges and solutions.Clinical and experimental gastroenterology · 2019Review
- Genetic Variation and Gene Expression Levels of Tight Junction Genes Indicates Relationships Between PTEN as well as MAGI1 and Microscopic Colitis.Digestive diseases and sciences · 2018Article
- Case-Control Comparison of Enteric Viromes in Captive Rhesus Macaques with Acute or Idiopathic Chronic Diarrhea.Journal of virology · 2017Article
- Proton pump inhibitor induced collagen expression in colonocytes is associated with collagenous colitis.World journal of gastroenterology · 2017Article
- Drug Exposure and the Risk of Microscopic Colitis: A Critical Update.Drugs in R&D · 2017Review
- Review: chronic and persistent diarrhea with a focus in the returning traveler.Tropical diseases, travel medicine and vaccines · 2017Review
- Biomarkers and Microscopic Colitis: An Unmet Need in Clinical Practice.Frontiers in medicine · 2017Review
- Microscopic Colitis After Fecal Microbiota Transplant.ACG case reports journal · 2017Article
- Shedding light on the dark side of microscopic colitis.Techniques in coloproctology · 2016Article
- Microscopic colitis that is not so microscopic.International journal of colorectal disease · 2016Article
- Pharmacologic Agents for Chronic Diarrhea.Intestinal research · 2015Review
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microscopic colitis (MC) is characterized by chronic, watery, secretory diarrhea, with a normal or near normal gross appearance of the colonic mucosa. Biopsy is diagnostic and usually reveals either lymphocytic colitis or collagenous colitis. The symptoms of collagenous colitis appear most commonly in the sixth decade. Patients report watery, nonbloody diarrhea of a chronic, intermittent or chronic recurrent course. With collagenous colitis, the major microscopic characteristic is a thickened collagen layer beneath the colonic mucosa, and with lymphocytic colitis, an increased number of intraepithelial lymphocytes. Histological workup can confirm a diagnosis of MC and distinguish the two distinct histological forms, namely, collagenous and lymphocytic colitis. Presently, both forms are diagnosed and treated in the same way; thus, the description of the two forms is not of clinical value although this may change in the future. Since microscopic colitis was first described in 1976 and only recently recognized as a common cause of diarrhea, many practicing physicians may not be aware of this entity. In this review, we outline the epidemiology, risk factors associated with MC, its etiopathogenesis, the approach to diagnosis and the management of these individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.