ArticleDisease markers2014
Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss.
Article in Disease markers, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association Between Hematological Indices of Inflammation and Pathogenesis and Prognosis of Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-Analysis.The journal of international advanced otology · 2025Pooled it
- Relationship between platelet parameters and sudden sensorineural hearing loss: a systematic review and meta-analysis.Bioscience reports · 2018Pooled it
- Pooled it
- The relationship of high-frequency distortion product otoacoustic emission (DPOAE) values with hematological parameters in tinnitus patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Trial
- Selected Blood Inflammatory and Metabolic Parameters Predicted Successive Bilateral Sudden Sensorineural Hearing Loss.Disease markers · 2019Trial
- Significance of Systemic Immune-Inflammation and Inflammatory Response Indices in Vestibular Neuritis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026Article
- A prognostic nomogram for all frequencies sudden sensorineural hearing loss based on the commixed index of inflammatory-immune-hemostasis-nutrition.Scientific reports · 2026Article
- Association between baseline neutrophil-to-lymphocyte ratio and short-term hearing recovery after glucocorticoid therapy in idiopathic sudden sensorineural hearing loss.Frontiers in medicine · 2026Article
- Relationship between different blood routine parameters and different types of sudden deafness and prognosis.Frontiers in medicine · 2025Article
- Risk Factors for Sensorineural Hearing Loss in Children and Adolescents with Sickle Cell Disease.Iranian journal of otorhinolaryngology · 2025Article
- Evaluation of Prognostic Scores in Adult Patients with Idiopathic Sudden Hearing Loss.Journal of clinical practice and research · 2024Article
- Article
- Causal associations of white blood cell count and sudden sensorineural hearing loss: a bidirectional and multivariable Mendelian randomization study.Frontiers in neurology · 2024Article
- Etiological analysis of patients with sudden sensorineural hearing loss: a prospective case-control study.Scientific reports · 2023Article
- Characteristics and prognostic analysis of simultaneous bilateral sudden sensorineural hearing loss.Frontiers in neurology · 2023Article
- Comorbidities and laboratory changes of sudden sensorineural hearing loss: a review.Frontiers in neurology · 2023Review
- Examination of the Relation Between Audiometric Configuration and Hematological Parameters in Idiopathic Sudden Sensorineural Hearing Loss.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Circulatory disturbance of the cochlear spiral modiolar artery in a type 2 diabetic mouse model.Laryngoscope investigative otolaryngology · 2022Article
- Delayed Recovery in Idiopathic Sudden Sensorineural Hearing Loss.Journal of clinical medicine · 2022Article
- Neutrophil-lymphocyte ratio as a predictor of adverse outcome in patients with community-acquired pneumonia: A systematic review.Health science reports · 2022Review
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aim to provide useful evidence about the association of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with idiopathic sudden sensorineural hearing loss (ISSNHL) and its possibility of emerging as a cheap, reliable, and independent prognostic marker of ISSNHL.
methods348 patients diagnosed with ISSNHL were included in our retrospective data analysis. Blood samples and the hearing assessments of the patients were carried out. Then, the patients were divided into 2 groups as "recovered" and "unrecovered" according to their response to the treatment.
resultsBoth mean NLR and PLR values of the ISSNHL patients were significantly higher than the control group (both P < 0.001). The NLR value was 5.98 ± 4.22 in the unrecovered group and 3.50 ± 3.38 in the recovered group (P < 0.001). After adjustment in a binary logistic regression model, only NLR value was associated with the recovery of ISSNHL (P = 0.001). DISCUSSION: We demonstrated for the first time that NLR and PLR values were significantly high in ISSNHL patients. Also the NLR level might be taken into account as a novel potential marker to predict the patients' prognosis in terms of recovery.
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