ArticleOccupational and environmental medicine2014
Respiratory symptoms and lung function abnormalities related to work at a flavouring manufacturing facility.
Article in Occupational and environmental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Impact of Epidemic Intelligence Service Training in Occupational Respiratory Epidemiology.ATS scholar · 2023Article
- Increased oxidative stress responses in murine macrophages exposed at the air-liquid interface to third- and fourth-generation electronic nicotine delivery system (ENDS) aerosols.Toxicology reports · 2023Article
- Environmental and occupational bronchiolitis obliterans: new reality.EBioMedicine · 2023Review
- Two-year follow-up of exposure, engineering controls, respiratory protection and respiratory health among workers at an indium-tin oxide (ITO) production and reclamation facility.Occupational and environmental medicine · 2022Article
- Article
- Decrements in lung function and respiratory abnormalities associated with exposure to diacetyl and 2,3-pentanedione in coffee production workers.Frontiers in public health · 2022Article
- A Methodology for Harmonizing Safety and Health Scales in Occupational Risk Assessment.International journal of environmental research and public health · 2021Article
- Case Report: Flavoring-Related Lung Disease in a Coffee Roasting and Packaging Facility Worker With Unique Lung Histopathology Compared With Previously Described Cases of Obliterative Bronchiolitis.Frontiers in public health · 2021Article
- Occupational Bronchiolitis: An Update.Clinics in chest medicine · 2020Review
- An update on controversies in e-cigarettes.Paediatric respiratory reviews · 2020Review
- Acute Eosinophilic Pneumonia Due to Vaping-Associated Lung Injury.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2020Article
- Spirometric Abnormalities and Lung Function Decline in Current and Former Microwave Popcorn and Current Flavoring Manufacturing Workers.Journal of occupational and environmental medicine · 2020Article
- NIOSH's Respiratory Health Division: 50 years of science and service.Archives of environmental & occupational health · 2019Article
- Burden of respiratory abnormalities in microwave popcorn and flavouring manufacturing workers.Occupational and environmental medicine · 2018Article
- Article
- Pulmonary toxicity of e-cigarettes.American journal of physiology. Lung cellular and molecular physiology · 2017Review
- Article
- Respiratory morbidity in a coffee processing workplace with sentinel obliterative bronchiolitis cases.American journal of industrial medicine · 2015Article
- Occupational and environmental bronchiolar disorders.Seminars in respiratory and critical care medicine · 2015Review
- Electronic Cigarettes: Vulnerability of Youth.Pediatric allergy, immunology, and pulmonology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo better understand respiratory symptoms and lung function in flavouring manufacturing workers.
methodsWe offered a questionnaire and lung function testing to the current workforce of a flavouring manufacturing facility that had transitioned away from diacetyl and towards substitutes in recent years. We examined symptoms, spirometric parameters and diffusing capacity measurements by exposure variables, including facility tenure and time spent daily in production areas. We used linear and logistic regression to develop final models adjusted for age and smoking status.
resultsA total of 367 (93%) current workers participated. Shortness of breath was twice as common in those with tenure ≥ 7 years (OR 2.0, 95% CI 1.1 to 3.6). Other chest symptoms were associated with time spent daily in production. Participants who spent ≥ 1 h daily in production areas had twice the odds of any spirometric abnormality (OR 2.3; 95% CI 1.1 to 5.3) and three times the odds of low diffusing capacity (OR 2.8; 95% CI 0.9 to 9.4) than other participants. Mean spirometric parameters were significantly lower in those with tenure ≥ 7 years and those who spent ≥ 1 h daily in production. Mean diffusing capacity parameters were significantly lower in those with tenure ≥ 7 years. Differences in symptoms and lung function could not be explained by age, smoking status or employment at another flavouring plant.
conclusionsSymptoms and lung function findings were consistent with undiagnosed or subclinical obliterative bronchiolitis and associated with workplace exposures. Further efforts to lower exposures to flavouring chemicals, including diacetyl substitutes, are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.