Evidence map›Paper›PMID 24890818›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2014

A seroprevalence study of primate workers for asymptomatic rhesus cytomegalovirus infection.

J Jason Bowman, Peter D Burbelo, Rachel B Gill, Michael A Sauri, James M Schmitt, Jeffrey I Cohen

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

J Jason BowmanMedical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Peter D BurbeloNeurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, United States.
Rachel B GillMedical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Michael A SauriOccupational Health Consultants, Rockville, MD, United States.
James M SchmittOccupational Medical Service, Division of Occupational Safety and Health, Office of the Director, National Institutes of Health, Bethesda, MD, United States.
Jeffrey I CohenMedical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States. Electronic address: jcohen@niaid.nih.gov.
National Institute of Allergy and Infectious Diseases · USNational Institute of Dental and Craniofacial Research · USNational Institutes of Health · USOffice of the Director · USOphthalmology Consultants · US

Funding

Herpesvirus Pathogenesis and Vaccine DevelopmentZIAAI000978 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI COHEN, JEFFREY · 2009 to 2025
$13.7M
Pathogenesis and Chemotherapy of Human Virus InfectionsZIAAI000058 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI COHEN, JEFFREY · 2009 to 2025
$8.8M
Herpesvirus Pathogenesis and Vaccine DevelopmentZ01AI000978 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI COHEN, JEFFREY · 2006 to 2008
$680k
Intramural NIH HHS Z01 AI000978
6 · The paper itself

Abstract

backgroundHuman cytomegalovirus (HCMV) infection can cause severe disease in neonates and immunocompromised persons, and infectious mononucleosis in healthy adults. While, rhesus CMV (RhCMV) infects human cells in culture, it is unknown whether the virus can infect humans.

objectivesWe sought to determine whether primate workers, including those with injuries from animals, might be infected asymptomatically with RhCMV. STUDY

designWe developed serologic assays that distinguish RhCMV from HCMV antibodies. We tested two groups of primate workers: those with documented injuries or mucosal splashes associated with rhesus macaques, and those with no documented exposure who worked with these animals.

resultsNone of over 200 primate workers, including 119 with injuries or mucosal splashes associated with exposures to macaques, were seropositive for RhCMV.

conclusionsThe frequency of asymptomatic RhCMV infection in persons who work with rhesus macaques was <0.5% (<1/200 primate workers).

Indexed as

AnimalsAsymptomatic DiseasesBites and StingsCytomegalovirusCytomegalovirus InfectionsHumansMacaca mulattaMonkey DiseasesOccupational ExposureSeroepidemiologic StudiesCytomegalovirusPrimate workersRhesus cytomegalovirusZoonosis

Identifiers

PMID24890818
PMCPMC4111921
OpenAlexW2017771263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.