Evidence map›Paper›PMID 24890678›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2014

Stem cells loaded with nanoparticles as a drug carrier for in vivo breast cancer therapy.

Binrui Cao, Mingying Yang, Ye Zhu, Xuewei Qu, Chuanbin Mao

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 111 citations in OpenAlex.

  1. Review
  2. Article
  3. 3D nanocomposites of β-TCP-HScientific reports · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Human Mesenchymal Stem Cells as a Carrier for a Cell-Mediated Drug Delivery.Frontiers in bioengineering and biotechnology · 2022
    Article
  13. Review
  14. Review
  15. Review
  16. [Progress on utilizing mesenchymal stem cells as cellular delivery system for targeting delivery of as drug/gene for anti-tumor therapy].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2020
    Review
  17. Review
  18. Enhancement of Photodynamic Cancer Therapy by Physical and Chemical Factors.Angewandte Chemie (International ed. in English) · 2019
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Binrui CaoDepartment of Chemistry & Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, 101 Stephenson Parkway, Norman, OK, 73019-5251, USA.
Mingying Yang
Ye Zhu
Xuewei Qu
Chuanbin Mao
University of Oklahoma · USZhejiang University · CN

Funding

Phage-inspired nanoparticles with genetically tunable target-specificityR01HL092526 · NHLBI · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2010
$806k
Phage-Mimetic Nanorods for Targeted Breast Cancer TreatmentR21EB009909 · NIBIB · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2009 to 2010
$399k
Tubulin-Binding Upconversion Nanoparticles for Breast-Cancer Imaging and TherapyR21EB015190 · NIBIB · UNIVERSITY OF OKLAHOMA · PI MAO, CHUANBIN · 2012 to 2013
$398k
NHLBI NIH HHS HL092526NHLBI NIH HHS R01 HL092526NIBIB NIH HHS EB009909NIBIB NIH HHS EB015190NIBIB NIH HHS R21 EB009909NIBIB NIH HHS R21 EB015190
6 · The paper itself

Abstract

A novel anti-cancer drug carrier, mesenchymal stem cells (MSCs) encapsulating drug-loaded hollow silica nanoparticles, is used to carry a photosensitizer drug and deliver it to breast tumors, due to the natural high tumor affinity of the MSCs, and inhibit tumor growth by photo dynamic therapy. This new strategy for delivering a photo sensitizer to tumors by using tumor-affinitive MSCs addresses the challenge of the accumulation of photosensitizer drugs in tumors in photodynamic therapy.

Indexed as

Mesenchymal Stem CellsBreast NeoplasmsCell Line, TumorDrug CarriersHumansMCF-7 CellsNanoparticlesPhotochemotherapyPhotosensitizing AgentsDrug CarriersPhotosensitizing Agentscancermesenchymal stem cells (MSCs)nanoparticlesphotodynamic therapyphotosensitizers

Identifiers

PMID24890678
PMCPMC4292873
OpenAlexW2134902598

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.