Evidence map›Paper›PMID 24890658›Full record

ArticleOrganic letters2014

Copper-catalyzed [18F]fluorination of (mesityl)(aryl)iodonium salts.

Naoko Ichiishi, Allen F Brooks, Joseph J Topczewski, Melissa E Rodnick, Melanie S Sanford, Peter J H Scott

Abstract read
In one paragraph

Article in Organic letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

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  3. Aryl Sulfamoyl [Journal of medicinal chemistry · 2026
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  10. Preparation ofPharmaceutics · 2023
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  11. Concise and Scalable Radiosynthesis of (+)-[ACS chemical neuroscience · 2023
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  12. Review
  13. Broad-scope Syntheses of [Chemistry (Weinheim an der Bergstrasse, Germany) · 2023
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  14. One-Pot Radiosynthesis of [Molecules (Basel, Switzerland) · 2023
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  15. Next Generation Copper Mediators for the Efficient Production ofChemistry (Weinheim an der Bergstrasse, Germany) · 2023
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  16. Fully automatedScientific reports · 2022
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  17. Recent Advances inPharmaceutics · 2022
    Review
  18. Isotopic Radiolabeling of the Antiretroviral Drug [Pharmaceuticals (Basel, Switzerland) · 2022
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  19. Nucleophilic Radiofluorination Using Tri-Molecules (Basel, Switzerland) · 2022
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  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naoko IchiishiDepartment of Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109, United States.
Allen F Brooks
Joseph J Topczewski
Melissa E Rodnick
Melanie S Sanford
Peter J H Scott

Funding

C-H Bond Functionalization in Organic SynthesisR01GM073836 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANFORD, MELANIE S. · 2005 to 2019
$4.0M
Training Future Imaging Scientists for BiomedicineT32EB005172 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FOWLKES, JEFFREY B · 2008 to 2012
$1.1M
NIBIB NIH HHS T32 EB005172NIBIB NIH HHS T32EB005172NIGMS NIH HHS GM073836NIGMS NIH HHS R01 GM073836
6 · The paper itself

Abstract

A practical, rapid, and highly regioselective Cu-catalyzed radiofluorination of (mesityl)(aryl)iodonium salts is described. This protocol utilizes [(18)F]KF to access (18)F-labeled electron-rich, -neutral, and -deficient aryl fluorides under a single set of mild conditions. This methodology is applied to the synthesis of protected versions of two important radiotracers: 4-[(18)F]fluorophenylalanine and 6-[(18)F]fluoroDOPA.

Indexed as

CatalysisCombinatorial Chemistry TechniquesCopperFluorine RadioisotopesHydrocarbons, FluorinatedMolecular StructureOnium CompoundsSaltsCopperFluorine RadioisotopesHydrocarbons, FluorinatedOnium CompoundsSalts

Identifiers

PMID24890658
PMCPMC4076000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.