Evidence map›Paper›PMID 24890513›Full record

ArticleCold Spring Harbor perspectives in biology2014

Epigenetic control of immunity.

Meinrad Busslinger, Alexander Tarakhovsky

Open access · bronzeAbstract read
In one paragraph

Article in Cold Spring Harbor perspectives in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 123 citations in OpenAlex.

  1. Trial
  2. Current issues in molecular biology · 2026
    Review
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  19. Epigenomic Profiling of B Cell Subsets by CUT&Tag.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  20. Review

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Meinrad BusslingerResearch Institute of Molecular Pathology, Vienna Biocenter, A-1030 Vienna, Austria.
Alexander TarakhovskyLaboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021.
Rockefeller University · USVienna Biocenter · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunity relies on the heterogeneity of immune cells and their ability to respond to pathogen challenges. In the adaptive immune system, lymphocytes display a highly diverse antigen receptor repertoire that matches the vast diversity of pathogens. In the innate immune system, the cell's heterogeneity and phenotypic plasticity enable flexible responses to changes in tissue homeostasis caused by infection or damage. The immune responses are calibrated by the graded activity of immune cells that can vary from yeast-like proliferation to lifetime dormancy. This article describes key epigenetic processes that contribute to the function of immune cells during health and disease.

Indexed as

Epigenesis, GeneticAdaptive ImmunityCell LineageHumansImmunityLymphocytes

Identifiers

PMID24890513
PMCPMC4031963
OpenAlexW2132056063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.