Trial reportJournal of neuroengineering and rehabilitation2014
Gait training early after stroke with a new exoskeleton--the hybrid assistive limb: a study of safety and feasibility.
Trial report in Journal of neuroengineering and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 74 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Gait Training Early After Stroke - a Comparison Between Training With the Exoskeleton Hybrid Assistive Limb and Conventional Gait Training
New Technology for Individualised, Intensive Training of Gait After Stroke- Phase II Trials, Study II
New Technology for Individualised, Intensive Training of Gait After Stroke- Phase II Trials, Study I
Who cites it
74 citing papers in PubMed, 4 syntheses or guidelines pooled it, 218 citations in OpenAlex.
- Control strategies used in lower limb exoskeletons for gait rehabilitation after brain injury: a systematic review and analysis of clinical effectiveness.Journal of neuroengineering and rehabilitation · 2023Pooled it
- Patient, carer, and staff perceptions of robotics in motor rehabilitation: a systematic review and qualitative meta-synthesis.Journal of neuroengineering and rehabilitation · 2021Pooled it
- Occurrence and Type of Adverse Events During the Use of Stationary Gait Robots-A Systematic Literature Review.Frontiers in robotics and AI · 2020Pooled it
- Powered robotic exoskeletons in post-stroke rehabilitation of gait: a scoping review.Journal of neuroengineering and rehabilitation · 2016Pooled it
- Activity-based training with the Myosuit: a safety and feasibility study across diverse gait disorders.Journal of neuroengineering and rehabilitation · 2020Trial
- Trial
- Hybrid assistive limb (HAL) treatment for patients with severe thoracic myelopathy due to ossification of the posterior longitudinal ligament (OPLL) in the postoperative acute/subacute phase: A clinical trial.The journal of spinal cord medicine · 2019Trial
- Shaping neuroplasticity by using powered exoskeletons in patients with stroke: a randomized clinical trial.Journal of neuroengineering and rehabilitation · 2018Trial
- Evaluating the effects of delivering integrated kinesthetic and tactile cues to individuals with unilateral hemiparetic stroke during overground walking.Journal of neuroengineering and rehabilitation · 2018Trial
- Effects on mobility training and de-adaptations in subjects with Spinal Cord Injury due to a Wearable Robot: a preliminary report.BMC neurology · 2016Trial
- The H2 robotic exoskeleton for gait rehabilitation after stroke: early findings from a clinical study.Journal of neuroengineering and rehabilitation · 2015Trial
- Comparative Analysis of Robotic Assistive Devices on Paretic Knee Motion in Post-Stroke Patients: An IMU-Based Pilot Study.Journal of functional morphology and kinesiology · 2025Article
- Rehabilitation training robot using mirror therapy for the upper and lower limb after stroke: a prospective cohort study.Journal of neuroengineering and rehabilitation · 2025Article
- Robot-assisted gait training in stroke.Turkish journal of physical medicine and rehabilitation · 2024Review
- Implementation of a unilateral hip flexion exosuit to aid paretic limb advancement during inpatient gait retraining for individuals post-stroke: a feasibility study.Journal of neuroengineering and rehabilitation · 2024Article
- Review of Vision-Based Environmental Perception for Lower-Limb Exoskeleton Robots.Biomimetics (Basel, Switzerland) · 2024Article
- Robotic exoskeleton-assisted walking rehabilitation for stroke patients: a bibliometric and visual analysis.Frontiers in bioengineering and biotechnology · 2024Review
- [Multi-modal synergistic quantitative analysis and rehabilitation assessment of lower limbs for exoskeleton].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- Evaluating the usability of a co-designed power assisted exercise graphical user interface for people with stroke.Journal of neuroengineering and rehabilitation · 2023Article
- Opportunities and challenges in the development of exoskeletons for locomotor assistance.Nature biomedical engineering · 2023Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntensive task specific training early after stroke may enhance beneficial neuroplasticity and functional recovery. Impaired gait after hemiparetic stroke remains a challenge that may be approached early after stroke by use of novel technology. The aim of the study was to investigate the safety and feasibility of the exoskeleton Hybrid Assistive Limb (HAL) for intensive gait training as part of a regular inpatient rehabilitation program for hemiparetic patients with severely impaired gait early after stroke.
methodsEligible were patients until 7 weeks after hemiparetic stroke. Training with HAL was performed 5 days per week by the autonomous and/or the voluntary control mode offered by the system. The study protocol covered safety and feasibility issues and aspects on motor function, gait performance according to the 10 Meter Walking Test (10MWT) and Functional Ambulation Categories (FAC), and activity performance.
resultsEight patients completed the study. Median time from stroke to inclusion was 35 days (range 6 to 46). Training started by use of the autonomous HAL mode in all and later switched to the voluntary mode in all but one and required one or two physiotherapists. Number of training sessions ranged from 6 to 31 (median 17) and walking time per session was around 25 minutes. The training was well tolerated and no serious adverse events occurred. All patients improved their walking ability during the training period, as reflected by the 10MWT (from 111.5 to 40 seconds in median) and the FAC (from 0 to 1.5 score in median).
conclusionsThe HAL system enables intensive training of gait in hemiparetic patients with severely impaired gait function early after stroke. The system is safe when used as part of an inpatient rehabilitation program for these patients by experienced physiotherapists.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.