ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2014
Risks of all-cause and suicide mortality in mental disorders: a meta-review.
Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 931 papers, 12 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Efficacy and Safety of Anodal Transcranial Direct Current Stimulation (TDCS) in Pediatric and Teenage Patients With Major Depressive Disorder During COVID-19 Pandemics
A Randomised Controlled Trial Evaluating the Efficacy and Mechanisms of a Ketogenic Diet as an Adjunctive Treatment for People With Treatment-resistant Depression
Presence of PTSD and Emotion Dysregulation Among Inpatients With Substance Use Disorder; a Feasibility Study of a Combined Treatment for Difficulties in Emotion Regulation and PTSD
Who cites it
931 citing papers in PubMed, 12 syntheses or guidelines pooled it, 2,056 citations in OpenAlex.
- Pooled it
- Multiancestry and Multitrait GWAS Meta-Analysis on Schizophrenia With a Sample of 322,321 Unveils Genetic Links to Chronic Lung Diseases.Genes, brain, and behavior · 2026Pooled it
- Multi-Trait Genetic Insights Into Schizophrenia Across Ancestries: Genome-Wide Association Meta-Analyses, Machine Learning, and Drug Repurposing Study.Brain and behavior · 2026Pooled it
- Efficacy and safety of pharmacological treatments in borderline personality disorder: A systematic review and network meta-analysis.Molecular psychiatry · 2026Pooled it
- The impact of premature birth and low birth weight on motor, visual, and cognitive skills and mental health in adolescence: a systematic review and meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- Systematic Review and Meta-Analysis of Mortality in Patients With Anorexia Nervosa.The International journal of eating disorders · 2026Pooled it
- Shared genetic underpinnings of gray matter volume alterations and metabolic traits in major depressive disorder.BMC psychiatry · 2026Pooled it
- 2025 Update to the Female Athlete Triad Coalition Consensus Statement Part 2: Clinical Guidelines for Screening, Diagnosis, Treatment, and Return to Play for Adolescents and Adults.Sports medicine (Auckland, N.Z.) · 2026Guideline
- Cluster headache suicidality: a systematic review with a meta-analysis.The journal of headache and pain · 2025Pooled it
- Pooled it
- Treatment effectiveness for comorbid anorexia nervosa and obsessive-compulsive disorder: a systematic review.International journal of psychiatry in clinical practice · 2025Pooled it
- Understanding the Autistic Experience of Restrictive Eating Disorders-A Systematic Review and Qualitative-Synthesis.European eating disorders review : the journal of the Eating Disorders Association · 2025Pooled it
- Training Clinicians in Private Practice in Family-Based Treatment for Anorexia Nervosa: Randomized Controlled Trial Comparing Two Online Approaches.Journal of medical Internet research · 2026Trial
- Trial
- Structural Brain Network Alterations in Relation to Treatment and Illness Severity in Bipolar Disorder.Biological psychiatry · 2026Article
- Cardiometabolic Treatment Gap in Routine Psychiatric Care: A Cross-Sectional Study of 1553 Patients.Acta psychiatrica Scandinavica · 2026Observational
- Environmentally relevant bis(2-ethylhexyl) phthalate exposure increases stress vulnerability, evoking depressive-like behaviors in male mice.Archives of toxicology · 2026Article
- Existing in a Battle Zone - The Lived Experience of Adolescents Subjected to Hospital Compulsory Care Due to Severe Anorexia Nervosa.Child psychiatry and human development · 2026Article
- Measuring and Characterizing Psychiatric Multimorbidity Among Individuals with Mental Illness.Community mental health journal · 2026Article
- [Patient navigation in severe mental illness-challenges, models, and perspectives].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026Review
871 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
A meta-review, or review of systematic reviews, was conducted to explore the risks of all-cause and suicide mortality in major mental disorders. A systematic search generated 407 relevant reviews, of which 20 reported mortality risks in 20 different mental disorders and included over 1.7 million patients and over a quarter of a million deaths. All disorders had an increased risk of all-cause mortality compared with the general population, and many had mortality risks larger than or comparable to heavy smoking. Those with the highest all-cause mortality ratios were substance use disorders and anorexia nervosa. These higher mortality risks translate into substantial (10-20 years) reductions in life expectancy. Borderline personality disorder, anorexia nervosa, depression and bipolar disorder had the highest suicide risks. Notable gaps were identified in the review literature, and the quality of the included reviews was typically low. The excess risks of mortality and suicide in all mental disorders justify a higher priority for the research, prevention, and treatment of the determinants of premature death in psychiatric patients.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.