Evidence map›Paper›PMID 24889954›Full record

ArticleHealth affairs (Project Hope)2014

CDC central-line bloodstream infection prevention efforts produced net benefits of at least $640 Million during 1990-2008.

R Douglas Scott, Ronda Sinkowitz-Cochran, Matthew E Wise, James Baggs, Scott Goates, Steven L Solomon, L Clifford McDonald, John A Jernigan

Abstract read
In one paragraph

Article in Health affairs (Project Hope), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Eliminating Infections in the ICU: CLABSI.Current infectious disease reports · 2015
    Article
  7. Article
  8. Understanding the Economic Impact of Health Care-Associated Infections: A Cost Perspective Analysis.Journal of infusion nursing : the official publication of the Infusion Nurses Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 6 countries.

R Douglas ScottR. Douglas Scott II (DScott1@cdc.gov) is an economist in the Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention (CDC), in Atlanta, Georgia.
Ronda Sinkowitz-CochranRonda Sinkowitz-Cochran is a behavioral scientist in the Division of Healthcare Quality Promotion, CDC.
Matthew E WiseMatthew E. Wise is an epidemiologist in the Division of Foodborne, Waterborne, and Environmental Diseases, CDC.
James BaggsJames Baggs is an epidemiologist in the Division of Healthcare Quality Promotion, CDC.
Scott GoatesScott Goates was an economist in the Office of the Assistant Director for Policy, CDC, at the time of this research. He is now health economics and outcomes research manager, Abbott Nutrition, in Columbus, Ohio.
Steven L SolomonSteven L. Solomon is director of the Office of Antimicrobial Resistance, Division of Healthcare Quality Promotion, CDC.
L Clifford McDonaldL. Clifford McDonald is senior adviser for science and integrity, Division of Healthcare Quality Promotion, CDC.
John A JerniganJohn A. Jernigan is director of the Office of Prevention Research and Evaluation, Division of Healthcare Quality Promotion, CDC.
Centers for Disease Control and Prevention · USClifford Chance · GBHealth Economics and Outcomes Research (United Kingdom) · GBInternational Solomon University · UAJapan Community Healthcare Organization · JPNational Healthcare Service Center · HUSonic Healthcare (Germany) · DEWaterborne Environmental (United States) · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The prevention of central line-associated bloodstream infections in patients in hospital critical care units has been a target of efforts by the Centers for Disease Control and Prevention (CDC) since the 1960s. We developed a historical economic model to measure the net economic benefits of preventing these infections in Medicare and Medicaid patients in critical care units for the period 1990-2008-a time when reductions attributable to federal investment resulted primarily from CDC efforts-using the cost perspective of the federal government as a third-party payer. The estimated net economic benefits ranged from $640 million to $1.8 billion, with the corresponding net benefits per case averted ranging from $15,780 to $24,391. The per dollar rate of return on the CDC's investments ranged from $3.88 to $23.85. These findings suggest that investments in CDC programs targeting other health care-associated infections also have the potential to produce savings by lowering Medicare and Medicaid reimbursements.

Indexed as

BacteremiaCatheterization, Central VenousCatheters, IndwellingCenters for Disease Control and Prevention, U.S.Cost-Benefit AnalysisCost SavingsCross InfectionHealth ExpendituresHumansIntensive Care UnitsMedicaidMedicareModels, EconomicMonte Carlo MethodUnited StatesHealth EconomicsHealth SpendingHospitalsMedicaidMedicare

Identifiers

PMID24889954
PMCPMC12256127
OpenAlexW1998435649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.