Evidence map›Paper›PMID 24889662›Full record

GuidelineJapanese journal of radiology2014

Guidelines for the use of NBCA in vascular embolization devised by the Committee of Practice Guidelines of the Japanese Society of Interventional Radiology (CGJSIR), 2012 edition.

Yoshito Takeuchi, Hiroyuki Morishita, Yozo Sato, Shingo Hamaguchi, Noriaki Sakamoto, Hiroyuki Tokue, Takafumi Yonemitsu, Kenji Murakami, Hiroyasu Fujiwara, Keitaro Sofue and 5 more

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Japanese journal of radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Middle meningeal artery embolization with standalone or adjunctive coiling for treatment of chronic subdural hematoma: Systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Pooled it
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  7. Review
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  15. Rupture of a mediastinal collateral aneurysm associated with unilateral absence of pulmonary artery.Journal of vascular surgery cases and innovative techniques · 2025
    Article
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  19. The Use of Glue as an Embolic Agent in Trauma.Seminars in interventional radiology · 2025
    Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yoshito TakeuchiDepartment of Radiology, North Medical Center, Kyoto Prefectural University of Medicine, 481, Otokoyama, Yosanocho, Yosagun, Kyoto, 629-2261, Japan, yotake62@qg8.so-net.ne.jp.
Hiroyuki Morishita
Yozo Sato
Shingo Hamaguchi
Noriaki Sakamoto
Hiroyuki Tokue
Takafumi Yonemitsu
Kenji Murakami
Hiroyasu Fujiwara
Keitaro Sofue
Toshi Abe
Hideyuki Higashihara
Yasuo Nakajima
Morio Sato
Committee of Practice Guidelines of the Japanese Society of Interventional Radiology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanoacrylates are a group of fast-acting adhesives. They form low viscosity liquids in the monomer state and instantly polymerize to become adhesive upon contact with ionic substances. Since the 1950s, they have been used around the world for industrial and household purposes. N-butyl cyanoacrylate (NBCA) is a cyanoacrylate that is commonly used for medical care, and the closure of skin wounds with NBCA has been found to promote hemostasis. However, in Japan, the intravascular injection of NBCA is considered to be off-label use, except during the treatment of gastric varices under endoscopy. The use of NBCA in embolotherapy is considered when the target vessels cannot be cannulated superselectively, for vascular diseases that require long segments of the target vessel to be embolized, or for patients in a hypocoagulable state. NBCA-based embolotherapy can be used to treat vascular malformations, acute hemorrhaging, tumors, and venous disease. The complications associated with NBCA-based embolotherapy include tissue ischemia, hemorrhaging, systemic or local reactions, and catheter adhesion to blood vessels. NBCA is mixed with Lipiodol to make it radiopaque and to adjust its polymerization time. Since there are various technical aspects to performing NBCA-based embolotherapy safely, it should be carried out by, or with the assistance of, proficient interventional radiologists.

Indexed as

Embolization, TherapeuticEnbucrilateHumansJapanRadiology, InterventionalSocieties, MedicalVascular DiseasesVascular MalformationsEnbucrilate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.