ArticleProceedings of the National Academy of Sciences of the United States of America2014
Metabolomics and proteomics reveal impacts of chemically mediated competition on marine plankton.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 145 citations in OpenAlex.
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- Comparative Quantitative Proteomic Analysis of High and Low Toxin-ProducingMarine drugs · 2025Article
- Eco-evolutionary dynamics between multiple competitors reduce phytoplankton coexistence but have limited impacts on community productivity.Proceedings. Biological sciences · 2025Article
- Evolution Under Competition Increases Population Production by Reducing the Density-Dependence of Net Energy Fluxes and Growth.Ecology and evolution · 2025Article
- Biomass competition connects individual and community scaling patterns.Nature communications · 2024Article
- Progress and challenges in exploring aquatic microbial communities using non-targeted metabolomics.The ISME journal · 2023Review
- Precipitation, submarine groundwater discharge of nitrogen, and red tides along the southwest Florida Gulf coast.Heliyon · 2023Article
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- Flow cytometry-based study of model marine microalgal consortia revealed an ecological advantage of siderophore utilization by the dinoflagellateComputational and structural biotechnology journal · 2022Article
- Transcriptome and metabolome analyses of cold and darkness-induced pellicle cysts of Scrippsiella trochoidea.BMC genomics · 2021Article
- Brevetoxin and Conotoxin Interactions with Single-Domain Voltage-Gated Sodium Channels from a Diatom and Coccolithophore.Marine drugs · 2021Article
- Essential components of the xanthophyll cycle differ in high and low toxin Karenia brevis.Harmful algae · 2021Article
- Biochemical Characterization of a Novel Redox-Regulated Metacaspase in a Marine Diatom.Frontiers in microbiology · 2021Article
- Competitive traits of coral symbionts may alter the structure and function of the microbiome.The ISME journal · 2020Article
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- Quantitative Proteomic Profiling of Marine DiatomFrontiers in microbiology · 2020Article
- Bioengineering of Microalgae: Recent Advances, Perspectives, and Regulatory Challenges for Industrial Application.Frontiers in bioengineering and biotechnology · 2020Review
- Metabolic Insights Into Infochemicals Induced Colony Formation and Flocculation inFrontiers in microbiology · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Competition is a major force structuring marine planktonic communities. The release of compounds that inhibit competitors, a process known as allelopathy, may play a role in the maintenance of large blooms of the red-tide dinoflagellate Karenia brevis, which produces potent neurotoxins that negatively impact coastal marine ecosystems. K. brevis is variably allelopathic to multiple competitors, typically causing sublethal suppression of growth. We used metabolomic and proteomic analyses to investigate the role of chemically mediated ecological interactions between K. brevis and two diatom competitors, Asterionellopsis glacialis and Thalassiosira pseudonana. The impact of K. brevis allelopathy on competitor physiology was reflected in the metabolomes and expressed proteomes of both diatoms, although the diatom that co-occurs with K. brevis blooms (A. glacialis) exhibited more robust metabolism in response to K. brevis. The observed partial resistance of A. glacialis to allelopathy may be a result of its frequent exposure to K. brevis blooms in the Gulf of Mexico. For the more sensitive diatom, T. pseudonana, which may not have had opportunity to evolve resistance to K. brevis, allelopathy disrupted energy metabolism and impeded cellular protection mechanisms including altered cell membrane components, inhibited osmoregulation, and increased oxidative stress. Allelopathic compounds appear to target multiple physiological pathways in sensitive competitors, demonstrating that chemical cues in the plankton have the potential to alter large-scale ecosystem processes including primary production and nutrient cycling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.