ArticleCognitive, affective & behavioral neuroscience2014
Trauma exposure is associated with increased context-dependent adjustments of cognitive control in patients with posttraumatic stress disorder and healthy controls.
Article in Cognitive, affective & behavioral neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Cortisol, heart rate, and blood pressure as early markers of PTSD risk: A systematic review and meta-analysis.Clinical psychology review · 2016Pooled it
- Bias in hair cortisol measures for psychological stress: Self vs. professional collection.Psychoneuroendocrinology · 2026Article
- A systematic review of stress-adapted skills and hidden talents in individuals who faced early adversity.Development and psychopathology · 2025Article
- Inconclusive evidence for associations between adverse experiences in adulthood and working memory performance.Royal Society open science · 2025Article
- Conflict Adaptation in Aphasia: Upregulating Cognitive Control for Improved Sentence Comprehension.Journal of speech, language, and hearing research : JSLHR · 2024Article
- Cingulate-Prefrontal Connectivity During Dynamic Cognitive Control Mediates Association Between p Factor and Adaptive Functioning in a Transdiagnostic Pediatric Sample.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Lifetime Trauma History and Cognitive Functioning in Major Depression and Their Role for Cognitive-Behavioral Therapy Outcome.Clinical psychology in Europe · 2021Article
- The effects of induced and trait anxiety on the sequential modulation of emotional conflict.Psychological research · 2021Article
- Measuring Adaptive Control in Conflict Tasks.Trends in cognitive sciences · 2019Review
- Perceived control of anxiety as a moderator in the relationship between anxiety sensitivity and problematic alcohol use among adolescents.Journal of adolescence · 2018Article
- Behavioral and neural correlates of disrupted orienting attention in posttraumatic stress disorder.Cognitive, affective & behavioral neuroscience · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent evidence has suggested that posttraumatic stress disorder (PTSD) is associated with alterations in prefrontal-cortex-dependent cognitive processes (e.g., working memory, cognitive control). However, it remains unclear whether these cognitive dysfunctions are related to PTSD symptomatology or trauma exposure. Furthermore, regarding cognitive control, research has only focused on the integrity of selected control functions, but not their dynamic regulation in response to changing environmental demands. Therefore, the present study investigated dynamic variations in interference control, in addition to overall interference susceptibility and working memory (WM) performance in matched groups of 24 PTSD patients and 26 traumatized and 30 nontraumatized healthy controls. The Simon task was used to measure overall interference susceptibility and the flexible adjustment of cognitive control, on the basis of the occurrence of response conflicts (conflict adaptation effect). WM performance was assessed with the forward and backward digit span tasks. Since we have previously shown that trauma exposure per se is associated with reduced hair cortisol concentrations (HCC), we further explored whether PTSD/trauma-related cognitive alterations are related to HCC in proximal 3-cm hair segments. The results revealed that PTSD patients and traumatized controls showed significantly more pronounced conflict adaptation effects than nontraumatized controls. Moreover, the conflict adaptation effect was positively related to the number of lifetime traumatic events and the frequency of traumatization. The groups did not differ in overall interference susceptibility or WM performance. Exploratory analyses revealed no association between HCC and the observed cognitive differences. These results suggest that context-driven control adjustments constitute a sensitive correlate of trauma exposure, irrespective of PTSD.
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