ArticleBJOG : an international journal of obstetrics and gynaecology2014
Hypertension, snoring, and obstructive sleep apnoea during pregnancy: a cohort study.
Article in BJOG : an international journal of obstetrics and gynaecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01029691 (Use of PAP in Women With Pre-eclampsia), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of PAP in Women With Pre-eclampsia
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- The prevalence of obstructive sleep apnea and its association with pregnancy-related health outcomes: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2019Pooled it
- Positive Airway Pressure Treatment of Obstructive Sleep Apnea-Hypopnea in Hypertensive Disorders of Pregnancy: A Pilot Randomized Proof-of-Concept Clinical Trial.Annals of the American Thoracic Society · 2024Trial
- Effect of snoring on pregnant women and fetal outcomes: a cross sectional study.Sleep & breathing = Schlaf & Atmung · 2024Article
- Gestational intermittent hypoxia induces endothelial dysfunction and hypertension in pregnant rats: role of endothelin type B receptor†.Biology of reproduction · 2024Article
- Clinical application of a previously validated pregnancy-specific screening tool for sleep apnea in a cohort with a high prevalence of obesity.Sleep medicine: X · 2023Article
- Hypertensive disorders of pregnancy and risk of asthma and chronic obstructive pulmonary disease: a prospective cohort study.Lancet regional health. Americas · 2023Article
- Managing Pregnancy and Nursing Affecting African American Women with Inflammatory Bowel Disease: Clinical Outcomes and Parenthood.Medical research archives · 2023Article
- Continuous positive airway pressure treatment of obstructive sleep apnea and hypertensive complications in high-risk pregnancy.Sleep & breathing = Schlaf & Atmung · 2023Article
- Common sleep disorders in pregnancy: a review.Frontiers in medicine · 2023Review
- Determinants of non-completion of sleep apnea testing during pregnancy.Frontiers in sleep · 2023Article
- Spermidine Alleviates Intrauterine Hypoxia-Induced Offspring Newborn Myocardial Mitochondrial Damage in Rats by Inhibiting Oxidative Stress and Regulating Mitochondrial Quality Control.Iranian journal of pharmaceutical research : IJPR · 2022Article
- Obstructive sleep apnea in pregnant women.International anesthesiology clinics · 2022Article
- The effect of continuous positive airway pressure treatment on hypertensive disorder in pregnant women with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2022Article
- Sleep-Disordered Breathing in Pregnancy.Advances in experimental medicine and biology · 2022Article
- Fetal Heart Rate Decelerations in Women with Sleep-Disordered Breathing.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Snoring and depression symptoms in pregnant women.Sleep health · 2021Article
- Sleep-Disordered Breathing and Pregnancy-Related Cardiovascular Disease.Journal of women's health (2002) · 2021Review
- Treatment of superimposed preeclampsia on chronic hypertension in a twin pregnancy with automatic continuous positive airway pressure: a case report.BMC pulmonary medicine · 2020Article
- Sleep Disordered Breathing, a Novel, Modifiable Risk Factor for Hypertensive Disorders of Pregnancy.Current hypertension reports · 2020Review
- Sleep-disordered breathing does not impact maternal outcomes in women with hypertensive disorders of pregnancy.PloS one · 2020Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo assess the frequency of obstructive sleep apnoea among women with and without hypertensive disorders of pregnancy.
designCohort study.
settingObstetric clinics at an academic medical centre. POPULATION: Pregnant women with hypertensive disorders (chronic hypertension, gestational hypertension, or pre-eclampsia) and women who were normotensive.
methodsWomen completed a questionnaire about habitual snoring and underwent overnight ambulatory polysomnography.
main outcome measuresThe presence and severity of obstructive sleep apnoea.
resultsObstructive sleep apnoea was found among 21 of 51 women with hypertensive disorders (41%), but in only three of 16 women who were normotensive (19%, chi-square test, P=0.005). [Author correction added on 16 June 2014, after first online publication: Results mentioned in the abstract were amended.] Non-snoring women with hypertensive disorders typically had mild obstructive sleep apnoea, but >25% of snoring women with hypertensive disorders had moderate to severe obstructive sleep apnoea. Among women with hypertensive disorders, the mean apnoea/hypopnoea index was substantially higher in snorers than in non-snorers (19.9±34.1 versus 3.4±3.1, P=0.013), and the oxyhaemoglobin saturation nadir was significantly lower (86.4±6.6 versus 90.2±3.5, P=0.021). Among women with hypertensive disorders, after stratification by obesity, the pooled relative risk for obstructive sleep apnoea in snoring women with hypertension compared with non-snoring women with hypertension was 2.0 (95% CI 1.4-2.8).
conclusionsPregnant women with hypertension are at high risk for unrecognised obstructive sleep apnoea. Although longitudinal and intervention studies are urgently needed, given the known relationship between obstructive sleep apnoea and hypertension in the general population, it would seem pertinent that hypertensive pregnant women who snore should be tested for obstructive sleep apnoea, a condition believed to cause or promote hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.