ReviewPflugers Archiv : European journal of physiology2015
Mechanotransduction in the muscle spindle.
Review in Pflugers Archiv : European journal of physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
71 citing papers in PubMed.
- Cellular and molecular mechanisms of muscle spindle development and function.Physiology (Bethesda, Md.) · 2026Review
- Structural and Molecular Features of Human Extraocular Muscle Spindles Suggest a Unique Role in Proprioception.Investigative ophthalmology & visual science · 2026Article
- Histomorphological Effects of Repeated Administration of the TRPA1 Antagonist HC-030031 on Intrafusal and Extrafusal Muscle Fibers in Healthy Young Rats.Muscles (Basel, Switzerland) · 2026Article
- Classical Proprioceptors and Palisade Endings Have Distinct Molecular Profiles in Pig Eye Muscles.Investigative ophthalmology & visual science · 2026Article
- Exploring the proprioceptive potential of joint receptors using a biomimetic robotic joint.Scientific reports · 2026Article
- Duration-dependent effects of dry cupping on autonomic modulation and trapezius tissue compliance in smartphone users: a dose-finding study.Frontiers in physiology · 2026Article
- Computing muscle mechanical state variables from combined proprioceptive sensory feedback.Experimental physiology · 2025Article
- Firing properties of muscle spindle afferents in the intrinsic foot muscles and tactile afferents from the sole of the foot during upright stance.Experimental physiology · 2025Review
- Why is the muscle spindle so complicated?Experimental physiology · 2025Article
- Muscle spindle afferent neurons preferentially degenerate with aging.Scientific reports · 2025Article
- Effect of continuous Ia fibre activity suppression on hyperreflexia-related spasticity and maladaptive synaptic connections in the spinal cord after injury.Scientific reports · 2025Article
- Immunohistochemical Detection of Tentonin-3/TMEM150C in Human Dorsal Root Ganglion, Cutaneous End-Organ Complexes, and Muscle Spindles.Brain sciences · 2025Article
- A role for proprioceptors in sngception.Science advances · 2025Article
- Differential encoding of mammalian proprioception by voltage-gated sodium channels.Science advances · 2025Article
- Molecular and developmental insights into proprioceptive identity in the mesencephalic trigeminal nucleus neurons.Frontiers in cellular neuroscience · 2025Review
- Differential encoding of mammalian proprioception by voltage-gated sodium channels.bioRxiv : the preprint server for biology · 2024Article
- The 8:1:1 Supplementation of Branched-Chain Amino Acids in High-Intensity Training: A Case Study of the Protective Effect on Rhabdomyolysis.Healthcare (Basel, Switzerland) · 2024Article
- Biophysical model of muscle spindle encoding.Experimental physiology · 2024Review
- Genetic exploration of roles of acid-sensing ion channel subtypes in neurosensory mechanotransduction including proprioception.Experimental physiology · 2024Review
- There and back again: 50 years of wandering through terra incognita fusorum.Experimental physiology · 2024Review
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The focus of this review is on the principal sensory ending of the mammalian muscle spindle, known as the primary ending. The process of mechanosensory transduction in the primary ending is examined under five headings: (i) action potential responses to defined mechanical stimuli-representing the ending's input-output properties; (ii) the receptor potential-including the currents giving rise to it; (iii) sensory-terminal deformation-measurable changes in the shape of the primary-ending terminals correlated with intrafusal sarcomere length, and what may cause them; (iv) putative stretch-sensitive channels-pharmacological and immunocytochemical clues to their identity; and (v) synaptic-like vesicles-the physiology and pharmacology of an intrinsic glutamatergic system in the primary and other mechanosensory endings, with some thoughts on the possible role of the system. Thus, the review highlights spindle stretch-evoked output is the product of multi-ionic receptor currents plus complex and sophisticated regulatory gain controls, both positive and negative in nature, as befits its status as the most complex sensory organ after the special senses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.