Evidence map›Paper›PMID 24887807›Full record

ReviewLab on a chip2014

Magnetic sensing technology for molecular analyses.

D Issadore, Y I Park, H Shao, C Min, K Lee, M Liong, R Weissleder, H Lee

Abstract readReview
In one paragraph

Review in Lab on a chip, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Immunomagnetic microscopy of tumor tissues using quantum sensors in diamond.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Review
  18. MRI-based Glucose Assay Using Magnetic Nanoparticle Sensors.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

D IssadoreSchool of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA.
Y I Park
H Shao
C Min
K Lee
M Liong
R Weissleder
H Lee

Funding

The role of microvesicles in giloma virotherapyP01CA069246 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHAREST, ALAIN · 1996 to 2021
$30.9M
TREATMENT OF CANCER WITH siRNA DELVIERED BY NANOPARTICLESU54CA119349 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELCHER, ANGELA M. · 2005 to 2009
$20.5M
Dana Farber/Harvard Cancer Consortium Career Development Program in Clinical OncologyK12CA087723 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI David Tsai Ting · 2002 to 2026
$17.9M
Training Grant in Molecular Imaging Research (MGH/HMS)T32CA079443 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2000 to 2025
$10.1M
Magnetic nanoswitches for sensing biomoleculesR01EB004626 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2004 to 2012
$3.2M
Novel Clickdyes for Biomedical SensingR01EB010011 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2010 to 2017
$3.1M
MAGNETIC NANOSENSORS FOR BIOMEDICAL ANALYSES OF MICROVESICLESR01HL113156 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO · 2012 to 2016
$2.1M
A micro Hall chip for circulating microvesicle based cancer monitoringR21CA182336 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ISSADORE, DAVID AARON · 2014 to 2016
$664k
NCI NIH HHS K12 CA087723NCI NIH HHS K12CA087723-09NCI NIH HHS P01 CA069246NCI NIH HHS R21 CA182336NCI NIH HHS T32 CA079443NCI NIH HHS T32-CA79443NCI NIH HHS U54 CA119349NCI NIH HHS U54-CA119349NHLBI NIH HHS HHSN268201000044CNHLBI NIH HHS R01 HL113156NHLBI NIH HHS R01HL113156NIBIB NIH HHS R01 EB004626NIBIB NIH HHS R01EB004626NIBIB NIH HHS R01 EB010011NIBIB NIH HHS R01EB010011
6 · The paper itself

Abstract

Magnetic biosensors, based on nanomaterials and miniature electronics, have emerged as a powerful diagnostic platform. Benefiting from the inherently negligible magnetic background of biological objects, magnetic detection is highly selective even in complex biological media. The sensing thus requires minimal sample purification and yet achieves a high signal-to-background contrast. Moreover, magnetic sensors are also well-suited for miniaturization to match the size of biological targets, which enables sensitive detection of rare cells and small amounts of molecular markers. We herein summarize recent advances in magnetic sensing technologies, with an emphasis on clinical applications in point-of-care settings. Key components of sensors, including magnetic nanomaterials, labeling strategies and magnetometry, are reviewed.

Indexed as

Biosensing TechniquesMagnetometryNanostructures

Identifiers

PMID24887807
PMCPMC4098149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.