Evidence map›Paper›PMID 24887579›Full record

Trial reportJournal of cardiac failure2014

Associations between seattle heart failure model scores and medical resource use and costs: findings from HF-ACTION.

Yanhong Li, Wayne C Levy, Matthew P Neilson, Stephen J Ellis, David J Whellan, Kevin A Schulman, Christopher M O'Connor, Shelby D Reed

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of cardiac failure, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yanhong LiDuke Clinical Research Institute, Durham, North Carolina.
Wayne C LevyUniversity of Washington School of Medicine, Seattle, Washington.
Matthew P NeilsonDepartment of Medicine, Duke University School of Medicine, Durham, North Carolina; University of Glasgow, Glasgow, Scotland.
Stephen J EllisDuke Clinical Research Institute, Durham, North Carolina.
David J WhellanDepartment of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Kevin A SchulmanDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Christopher M O'ConnorDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Shelby D ReedDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina. Electronic address: shelby.reed@duke.edu.

Funding

ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL063747 · NHLBI · DUKE UNIVERSITY · PI O'CONNOR, CHRISTOPHER M · 2002 to 2008
$24.8M
Exercise Intolerance in Elderly Diastolic Heart FailureR37AG018915 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2005 to 2013
$3.4M
THERAPEUTIC EXERCISE FOR KNEE OSTEOARTHRITISP60AG010484 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 1991 to 2002
$3.1M
ACTION EQOL STUDYU01HL066461 · NHLBI · DUKE UNIVERSITY · PI SCHULMAN, KEVIN ALAN · 2002 to 2008
$2.7M
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL064250 · NHLBI · HENRY FORD HEALTH SYSTEM · PI KETEYIAN, STEVEN J · 2002 to 2007
$1.4M
CHF TRIAL INVESTIGATING OUTCOMES OF EXERCISE TRAININGU01HL066491 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2002 to 2007
$1.4M
Tools for Economic Analysis of Patient Management Interventions in Heart FailureR01NR011873 · NINR · DUKE UNIVERSITY · PI REED, SHELBY DERENE · 2009 to 2011
$1.2M
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL064264 · NHLBI · WASHINGTON UNIVERSITY · PI EWALD, GREGORY A · 2002 to 2006
$1.0M
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL068973 · NHLBI · BOSTON MEDICAL CENTER · PI COLUCCI, WILSON S. · 2002 to 2007
$1.0M
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL066501 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI PINA, ILEANA L · 2002 to 2007
$973k
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL066497 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BITTNER, VERA A · 2002 to 2005
$838k
ACTION - A CHF Trial Investigating Outcomes of ExerciseU01HL064257 · NHLBI · OREGON HEALTH AND SCIENCE UNIVERSITY · PI ALHARETHI, RAMI · 2002 to 2005
$773k
NHLBI NIH HHS 5U01HL063747NHLBI NIH HHS 5U01HL064250NHLBI NIH HHS 5U01HL064257NHLBI NIH HHS 5U01HL064264NHLBI NIH HHS 5U01HL064265NHLBI NIH HHS 5U01HL066461NHLBI NIH HHS 5U01HL066482NHLBI NIH HHS 5U01HL066491NHLBI NIH HHS 5U01HL066494NHLBI NIH HHS 5U01HL066497NHLBI NIH HHS 5U01HL066501NHLBI NIH HHS 5U01HL068973NHLBI NIH HHS 5U01HL068980NHLBI NIH HHS U01 HL063747NHLBI NIH HHS U01 HL064250NHLBI NIH HHS U01 HL064257NHLBI NIH HHS U01 HL064264NHLBI NIH HHS U01 HL064265NHLBI NIH HHS U01 HL066461NHLBI NIH HHS U01 HL066482NHLBI NIH HHS U01 HL066491NHLBI NIH HHS U01 HL066494NHLBI NIH HHS U01 HL066497NHLBI NIH HHS U01 HL066501NHLBI NIH HHS U01 HL068973NHLBI NIH HHS U01 HL068980NIA NIH HHS P60AG010484NIA NIH HHS R37 AG018915NIA NIH HHS R37AG018915NINR NIH HHS 5R01NR011873-02NINR NIH HHS R01 NR011873
6 · The paper itself

Abstract

backgroundPrognostic models, such as the Seattle Heart Failure Model (SHFM), have been developed to predict patient survival. The extent to which they predict medical resource use and costs has not been explored. In this study, we evaluated relationships between baseline SHFM scores and 1-year resource use and costs using data from a clinical trial. METHODS AND

resultsWe applied generalized linear models to examine the relative impact of a 1-unit increase in SHFM scores on counts of medical resource use and direct medical costs at 1 year of follow-up. Of 2331 randomized patients, 2288 (98%) had a rounded integer SHFM score between -1 and 2, consistent with predicted 1-year survival of 98% and 74%, respectively. At baseline, median age was 59 years, 28% of patients were women, and nearly two-thirds of the cohort had New York Heart Association class II heart failure and one-third had class III heart failure. Higher SHFM scores were associated with more hospitalizations (rate ratio per 1-unit increase, 1.86; P < .001), more inpatient days (2.30; P < .001), and higher inpatient costs (2.28; P < .001), outpatient costs (1.54; P < .001), and total medical costs (2.13; P < .001).

conclusionAlthough developed to predict all-cause mortality, SHFM scores also predict medical resource use and costs.

Indexed as

Health StatusAgedCanadaCosts and Cost AnalysisExercise TherapyFemaleFollow-Up StudiesFranceHealth ResourcesHeart FailureHumansLinear ModelsMaleMiddle AgedPrognosisRetrospective StudiesHealth care costshealth resourceshealth statusheart failurequestionnairesrisk assessment

Identifiers

PMID24887579
PMCPMC4138128

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.