ReviewFrontiers in neuroendocrinology2014
Sex differences in anxiety and depression clinical perspectives.
Review in Frontiers in neuroendocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 705 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
705 citing papers in PubMed, 3 syntheses or guidelines pooled it, 1,377 citations in OpenAlex.
- The impact of orthognathic surgery on oral function-related quality of life: a systematic review.Oral and maxillofacial surgery · 2025Pooled it
- ADHD and Suicidality in Adolescents: A Systematic Review of Moderators and Mediators.Clinical child and family psychology review · 2025Pooled it
- Sex-stratified genome-wide association meta-analysis of major depressive disorder.Nature communications · 2025Pooled it
- Gender differences in the influence of app-based mindfulness meditation on emotion regulation: a randomised controlled trial.Scientific reports · 2026Trial
- Sex Differences in Psychosocial Factors and Angina in Patients With Chronic Coronary Disease.Journal of the American Heart Association · 2025Trial
- Exercise interventions and presentations of depression and anxiety in male genitourinary cancer survivors: A scoping review.European journal of epidemiology · 2026Article
- Differential burden of five major mental disorders in the United States across the COVID-19 pandemic.European archives of psychiatry and clinical neuroscience · 2026Article
- On the importance of including both sexes in animal studies - insights from home-cage monitoring.Biological reviews of the Cambridge Philosophical Society · 2026Review
- The monocyte-to-HDL cholesterol ratio (MHR) modifies the association between dietary patterns and depression: a sex-specific analysis.European archives of psychiatry and clinical neuroscience · 2026Article
- Sex differences in subjective cognitive impairment among Chinese patients with depression: A large-scale cross-sectional study.General psychiatry · 2026Article
- National prevalence and sociodemographic correlates of potential depression, anxiety, and suicidality among the young population in Kazakhstan: a national population-based study.BMC psychology · 2026Article
- The Effects of Autonomy-Enhancing Therapy for Eating Disorders: Protocol for a Single-Case Experimental Multiple Baseline Design.JMIR research protocols · 2026Article
- SEX-DEPENDENT MODULATION OF WHOLE BRAIN cFOS EXPRESSION BY LIGHT AND MELANOPSIN IN THE MOUSE.bioRxiv : the preprint server for biology · 2026Article
- Women in space: A review of known physiological adaptations and health perspectives.Experimental physiology · 2026Review
- Executive Functioning Is Linked to Internalizing Symptoms in Autistic Adults With Higher Support Needs.Autism : the international journal of research and practice · 2026Article
- Proenkephalin neurons in the adBNST mitigate stress-induced anxiety and estrous cycle disruption in female mice.Neurobiology of stress · 2026Article
- Multilevel sex-influenced neurobiological signatures of early life adversity.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Synaptic Actions of Estradiol in the Brain's Reward System: Linking Mechanisms to Behavior and Disease.Biological psychiatry global open science · 2026Review
- Integrated Investigation of Sex Differences in the Human Nociceptin/Orphanin FQ Receptor System: Postmortem Analyses and In Vivo [Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Sex Differences in Oxidative Stress and Depression-Like Behavior Following Chronic Lead Exposure from Pregnancy to Adulthood.Biological trace element research · 2026Article
645 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Sex differences are prominent in mood and anxiety disorders and may provide a window into mechanisms of onset and maintenance of affective disturbances in both men and women. With the plethora of sex differences in brain structure, function, and stress responsivity, as well as differences in exposure to reproductive hormones, social expectations and experiences, the challenge is to understand which sex differences are relevant to affective illness. This review will focus on clinical aspects of sex differences in affective disorders including the emergence of sex differences across developmental stages and the impact of reproductive events. Biological, cultural, and experiential factors that may underlie sex differences in the phenomenology of mood and anxiety disorders are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.