Evidence map›Paper›PMID 24887217›Full record

ArticleBlood transfusion = Trasfusione del sangue2014

Incidence and pattern of 12 years of reported transfusion adverse events in Zimbabwe: a retrospective analysis.

Nyashadzaishe Mafirakureva, Star Khoza, David A Mvere, McLeod E Chitiyo, Maarten J Postma, Marinus Van Hulst

Open access · greenAbstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Paediatric anaphylaxis in South Africa.The World Allergy Organization journal · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Surveillance of Transfusion Related Adverse Reactions in a Tertiary Care Centre in Bangalore: A 4-Year Hemovigilance Initiative.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020
    Article
  9. Article
  10. Article
  11. Incidence and Analysis of 7 Years Adverse Transfusion Reaction: A Retrospective Analysis.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020
    Article
  12. Article
  13. Article
  14. Profiles of blood and blood component transfusion recipients in Zimbabwe.Blood transfusion = Trasfusione del sangue · 2015
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nyashadzaishe MafirakurevaUnit of Pharmaco-Epidemiology & Pharmaco-Economics (PE2), Department of Pharmacy, University of Groningen, Groningen, The Netherlands National Blood Service Zimbabwe, Harare, Zimbabwe.
Star KhozaDepartment of Clinical Pharmacology, College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
David A MvereNational Blood Service Zimbabwe, Harare, Zimbabwe.
McLeod E ChitiyoNational Blood Service Zimbabwe, Harare, Zimbabwe.
Maarten J PostmaUnit of Pharmaco-Epidemiology & Pharmaco-Economics (PE2), Department of Pharmacy, University of Groningen, Groningen, The Netherlands.
Marinus Van HulstUnit of Pharmaco-Epidemiology & Pharmaco-Economics (PE2), Department of Pharmacy, University of Groningen, Groningen, The Netherlands Department of Clinical Pharmacy and Toxicology, Martini Hospital, Groningen, The Netherlands.
National Blood Service Zimbabwe · ZWUniversity of Groningen · NLUniversity of Zimbabwe · ZW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHaemovigilance hinges on a systematically structured reporting system, which unfortunately does not always exist in resource-limited settings. We determined the incidence and pattern of transfusion-related adverse events reported to the National Blood Service Zimbabwe. MATERIALS AND

methodsA retrospective review of the transfusion-event records of the National Blood Service Zimbabwe was conducted covering the period from 1 January 1999 to 31 December 2011. All transfusion-related event reports received during the period were analysed.

resultsA total of 308 transfusion adverse events (0.046%) were reported for 670,625 blood components distributed. The majority (61.6%) of the patients who experienced an adverse event were female. The median age was 36 years (range, 1-89 years). The majority (68.8%) of the adverse events were acute transfusion reactions consisting of febrile non-haemolytic transfusion reactions (58.5%), minor allergies (31.6%), haemolytic reactions (5.2%), severe allergic reactions (2.4%), anaphylaxis (1.4%) and hypotension (0.9%). Two-thirds (66.6%) of the adverse events occurred following administration of whole blood, although only 10.6% of the blood was distributed as whole blood. Packed cells, which accounted for 75% of blood components distributed, were associated with 20.1% of the events. DISCUSSION: The incidence of suspected transfusion adverse events was generally lower than the incidences reported globally in countries with well-established haemovigilance systems. The administration of whole blood was disproportionately associated with transfusion adverse events. The pattern of the transfusion adverse events reported here highlights the probable differences in practice between different settings. Under-reporting of transfusion events is rife in passive reporting systems.

Indexed as

AnaphylaxisBlood SafetyHemolysisTransfusion ReactionAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansHypotensionInfantMaleMiddle Aged

Identifiers

PMID24887217
PMCPMC4111818
OpenAlexW188074231

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.