ArticlePloS one2014
Shared cognitive impairments and aetiology in ADHD symptoms and reading difficulties.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Are there shared neural correlates between dyslexia and ADHD? A meta-analysis of voxel-based morphometry studies.Journal of neurodevelopmental disorders · 2019Pooled it
- The underlying neuropsychological and neural correlates of the impaired Chinese reading skills in children with attention deficit hyperactivity disorder.European child & adolescent psychiatry · 2024Article
- Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? Incorporating a new neurodevelopmental spectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Reduced inhibition control ability in children with ADHD due to coexisting learning disorders: an fNIRS study.Frontiers in psychiatry · 2024Article
- Kynurenine and oxidative stress in children having learning disorder with and without attention deficit hyperactivity disorder: possible role and involvement.BMC neurology · 2022Article
- Polygenic risk for ADHD and ASD and their relation with cognitive measures in school children.Psychological medicine · 2022Article
- Is executive dysfunction a potential contributor to the comorbidity between basic reading disability and attention-deficit/hyperactivity disorder?Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2021Article
- Movement Patterns in Students Diagnosed with ADHD, Objective Measurement in a Natural Learning Environment.International journal of environmental research and public health · 2021Article
- Examining Distinctive Working Memory Profiles in Chinese Children With Predominantly Inattentive Subtype of Attention-Deficit/Hyperactivity Disorder and/or Reading Difficulties.Frontiers in psychology · 2021Article
- In Quest of Pathognomonic/Endophenotypic Markers of Attention Deficit Hyperactivity Disorder (ADHD): Potential of EEG-Based Frequency Analysis and ERPs to Better Detect, Prevent and Manage ADHD.Medical devices (Auckland, N.Z.) · 2020Review
- Delineating and validating higher-order dimensions of psychopathology in the Adolescent Brain Cognitive Development (ABCD) study.Translational psychiatry · 2019Article
- Current Pattern of Psychiatric Comorbidity and Psychotropic Drug Prescription in Child and Adolescent Patients.Medicina (Kaunas, Lithuania) · 2019Article
- Assessment of Psychiatric Comorbidity and WISC-R Profiles in Cases Diagnosed with Specific Learning Disorder According to DSM-5 Criteria.Noro psikiyatri arsivi · 2018Article
- Testing for the mediating role of endophenotypes using molecular genetic data in a twin study of ADHD traits.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2016Article
- Cognitive Function of Children and Adolescents with Attention Deficit Hyperactivity Disorder and Learning Difficulties: A Developmental Perspective.Chinese medical journal · 2016Article
- The aetiological association between the dynamics of cortisol productivity and ADHD.Journal of neural transmission (Vienna, Austria : 1996) · 2016Article
- Cognitive and neurophysiological markers of ADHD persistence and remission.The British journal of psychiatry : the journal of mental science · 2016Article
- Differences in the performance of NK1R-/- ('knockout') and wildtype mice in the 5‑Choice Continuous Performance Test.Behavioural brain research · 2016Article
Corrections and comments
- Erratum issuedFazier-Wood, Alexis C [corrected to Frazier-Wood, Alexis C]
Authors and funding
6 authors.
Funding
Abstract
backgroundTwin studies indicate that the frequent co-occurrence of attention deficit hyperactivity disorder (ADHD) symptoms and reading difficulties (RD) is largely due to shared genetic influences. Both disorders are associated with multiple cognitive impairments, but it remains unclear which cognitive impairments share the aetiological pathway, underlying the co-occurrence of the symptoms. We address this question using a sample of twins aged 7-10 and a range of cognitive measures previously associated with ADHD symptoms or RD.
methodsWe performed multivariate structural equation modelling analyses on parent and teacher ratings on the ADHD symptom domains of inattention and hyperactivity, parent ratings on RD, and cognitive data on response inhibition (commission errors, CE), reaction time variability (RTV), verbal short-term memory (STM), working memory (WM) and choice impulsivity, from a population sample of 1312 twins aged 7-10 years.
resultsThree cognitive processes showed significant phenotypic and genetic associations with both inattention symptoms and RD: RTV, verbal WM and STM. While STM captured only 11% of the shared genetic risk between inattention and RD, the estimates increased somewhat for WM (21%) and RTV (28%); yet most of the genetic sharing between inattention and RD remained unaccounted for in each case.
conclusionWhile response inhibition and choice impulsivity did not emerge as important cognitive processes underlying the co-occurrence between ADHD symptoms and RD, RTV and verbal memory processes separately showed significant phenotypic and genetic associations with both inattention symptoms and RD. Future studies employing longitudinal designs will be required to investigate the developmental pathways and direction of causality further.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.