ArticleCanadian journal of public health = Revue canadienne de sante publique2014
Non-medical prescription opioid use, prescription opioid-related harms and public health in Canada: an update 5 years later.
Article in Canadian journal of public health = Revue canadienne de sante publique, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prescription opioid epidemic: a review of qualitative studies on the progression from initial use to abuse.Dialogues in clinical neuroscience · 2017Pooled it
- Sensitivity to change of generic preference-based instruments (EQ-5D-3L, EQ-5D-5L, and HUI3) in the context of treatment for people with prescription-type opioid use disorder in Canada.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Trial
- Association of Opioid Consumption Profiles After Hospitalization With Risk of Adverse Health Care Events.JAMA network open · 2021Trial
- Article
- Treatment retention in opioid agonist therapy: comparison of methadone versus buprenorphine/naloxone by analysis of daily-witnessed dispensed medication in a Canadian Province.BMC psychiatry · 2022Article
- Trends in dispensing of individual prescription opioid formulations, Canada 2005-2020.Journal of pharmaceutical policy and practice · 2022Article
- Patterns, trends and determinants of medical opioid utilization in Canada 2005-2020: characterizing an era of intensive rise and fall.Substance abuse treatment, prevention, and policy · 2021Article
- The opioid mortality epidemic in North America: do we understand the supply side dynamics of this unprecedented crisis?Substance abuse treatment, prevention, and policy · 2020Article
- Overdose Risk and Acquiring Opioids for Nonmedical Use Exclusively from Physicians in Vancouver, Canada.Substance use & misuse · 2020Article
- The Surgeon's Role in the Opioid Crisis: A Narrative Review and Call to Action.Frontiers in surgery · 2020Review
- A gender-based analysis of nonmedical prescription opioid use among people who use illicit drugs.Addictive behaviors · 2019Article
- The risk of infective endocarditis among people who inject drugs: a retrospective, population-based time series analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019Article
- The OPTIMA study, buprenorphine/naloxone and methadone models of care for the treatment of prescription opioid use disorder: Study design and rationale.Contemporary clinical trials · 2018Article
- Epidemiologic trends in substance and opioid misuse-related emergency department visits in Alberta: a cross-sectional time-series analysis.Canadian journal of public health = Revue canadienne de sante publique · 2018Article
- Novel case of maternal and neonatal kratom dependence and withdrawal.Canadian family physician Medecin de famille canadien · 2018Article
- Increasing availability of illicit and prescription opioids among people who inject drugs in a Canadian setting, 2010-2014.The American journal of drug and alcohol abuse · 2018Article
- Prescription opioid use disorder and heroin use among 12-34 year-olds in the United States from 2002 to 2014.Addictive behaviors · 2017Article
- Effective Canadian policy to reduce harms from prescription opioids: learning from past failures.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2016Article
- Benzodiazepine Use, Misuse, and Harm at the Population Level in Canada: A Comprehensive Narrative Review of Data and Developments Since 1995.Clinical drug investigation · 2016Review
- Drug use patterns predict risk of non-fatal overdose among street-involved youth in a Canadian setting.Drug and alcohol dependence · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Five years ago, we highlighted Canada's emerging problem of prescription opioid (PO)-related harms and emphasized the need for targeted surveillance, research and interventions. Overall levels of PO use in the Canadian population have grown by 70% since then, while at the same time levels of non-medical PO use (NMPOU) in general and in key risk populations have continued to be high; furthermore, PO-related harms - specifically morbidity (e.g., treatment admissions) and mortality (e.g., overdose deaths) - have risen substantively. Unfortunately, major knowledge gaps related to systematic monitoring of PO-related harms continue to exist; for example, no national morbidity or mortality statistics are available. Investigator-driven research has generated important insights into the epidemiology and impacts of PO-related harms: high correlations between population-level PO dispensing and/or PO dosing and harms; high rates of co-occurrence of NMPOU and co-morbidities; and distinct NMPOU-related risk dynamics among street drug users. Select policy measures have been implemented only recently at the federal and provincial levels; these interventions remain to be systematically evaluated, especially given preliminary indications of reductions in PO-related harms (e.g., NMPOU) unfolding prior to the interventions. For these purposes, improvements in surveillance tools and research resources devoted to the extensive public health problem of PO-related harms in Canada continue to be urgently needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.