ArticleBMC genomics2014
Identification and characterization of microRNAs in the ovaries of multiple and uniparous goats (Capra hircus) during follicular phase.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Differential microRNA Expression Profiles in Girls with Idiopathic Central Precocious Puberty and Premature Thelarche.International journal of molecular sciences · 2026Article
- Gene regulation by non-Coding RNAs in infertility: a mechanistic review.Journal of ovarian research · 2025Review
- Whole Transcriptome Sequencing and Differential Analysis of Testes in Pre- and Post-Sexual MaturityBiology · 2025Article
- Article
- Identification and profiling of microRNAs during yak's testicular development.BMC veterinary research · 2023Article
- Integration of small RNA, degradome, and transcriptome sequencing data illustrates the mechanism of low phosphorus adaptation inFrontiers in plant science · 2022Article
- Expression characteristics of piRNAs in ovine luteal phase and follicular phase ovaries.Frontiers in veterinary science · 2022Article
- Integrated analyses of miRNA-mRNA expression profiles of ovaries reveal the crucial interaction networks that regulate the prolificacy of goats in the follicular phase.BMC genomics · 2021Article
- Epigenetic transgenerational inheritance, gametogenesis and germline development†.Biology of reproduction · 2021Review
- Differential Expression and Functional Analysis of CircRNA in the Ovaries of Low and High Fecundity Hanper Sheep.Animals : an open access journal from MDPI · 2021Article
- The Roles of the miRNAome and Transcriptome in the Ovine Ovary Reveal Poor Efficiency in Juvenile Superovulation.Animals : an open access journal from MDPI · 2021Article
- Article
- Comprehensive analysis of mRNAs and miRNAs in the ovarian follicles of uniparous and multiple goats at estrus phase.BMC genomics · 2020Article
- Effects of Decreasing Dietary Crude Protein Level on Growth Performance, Nutrient Digestion, Serum Metabolites, and Nitrogen Utilization in Growing Goat Kids (Animals : an open access journal from MDPI · 2020Article
- Comparative analysis of differentially expressed genes between the ovaries from pregnant and nonpregnant goats using RNA-Seq.Journal of biological research (Thessalonike, Greece) · 2019Article
- Non-coding RNA regulation in reproduction: Their potential use as biomarkers.Non-coding RNA research · 2019Review
- Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis.Oncology letters · 2019Article
- MicroRNAs in ovarian follicular atresia and granulosa cell apoptosis.Reproductive biology and endocrinology : RB&E · 2019Review
- Analyses of circRNA profiling during the development from pre-receptive to receptive phases in the goat endometrium.Journal of animal science and biotechnology · 2019Article
- Integrated analysis of mRNA and viral miRNAs in the kidney of Carassius auratus gibelio response to cyprinid herpesvirus 2.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuperior kidding rate is an important economic trait in production of meat goat, and ovulation rate is the precondition of kidding rate. MicroRNAs (miRNAs) play critical roles in almost all ovarian biological processes, including folliculogenesis, follicle development, follicle atresia, luteal development and regression. To find out the different ovarian activity and follicle recruitment with miRNA-mediated posttranscriptional regulation, the small RNAs expressed pattern in the ovarian tissues of multiple and uniparous Anhui White goats during follicular phase was analyzed using Solexa sequencing data.
results1008 miRNAs co-expressed, 309 and 433 miRNAs specifically expressed in the ovaries of multiple and uniparous goats during follicular phase were identified. The 10 most highly expressed miRNAs in the multiple library were also the highest expressed in the uniparous library, and there were no significantly different between each other. The highest specific expressed miRNA in the multiple library was miR-29c, and the one in the uniparous library was miR-6406. 35 novel miRNAs were predicted in total. GO annotation and KEGG Pathway analyses were implemented on target genes of all miRNA in two libraries. RT-PCR was applied to detect the expression level of 5 randomly selected miRNAs in multiple and uniparous hircine ovaries, and the results were consistent with the Solexa sequencing data.
conclusionsIn the present study, the different expression of miRNAs in the ovaries of multiple and uniparous goats during follicular phase were characterized and investigated using deep sequencing technology. The result will help to further understand the role of miRNAs in kidding rate regulation and also may help to identify miRNAs which could be potentially used to increase hircine ovulation rate and kidding rate in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.